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Resources in Evidence Repository and Individual Compendia

Clinical guidelines

Clinical Practice Guideline: AAOS clinical practice guideline: the treatment of pediatric diaphyseal femur fractures  (2009)

Clinical Practice Guideline: AAOS clinical practice guideline: the treatment of pediatric diaphyseal femur fractures

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Kocher, MS, Sink, EL, Blasier, RD, Luhmann, SJ, Mehlman, CT, Scher, DM, Matheney, T & Sanders, JO

Kocher, MS, Sink, EL, Blasier, RD, Luhmann, SJ, Mehlman, CT, Scher, DM, Mathe...

This is a summary of the recommendations in the AAOS clinical practice guideline, The Treatment of Pediatric Diaphyseal Femur Fractures.

This is a summary of the recommendations in the AAOS clinical practice guideline, The Treatment of Pediatric Diaphyseal Femur Fractures.

Clinical Practice Guidelines: Treatment of Distal Radius Fractures: Guideline and Evidence Report  (2009)

Clinical Practice Guidelines: Treatment of Distal Radius Fractures: Guideline and Evidence Report

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Lichtman DM, Randipsingh RR, Boyer MI, Putnam MD, Ring D, Slutsky DJ, Taras JS

Lichtman DM, Randipsingh RR, Boyer MI, Putnam MD, Ring D, Slutsky DJ, Taras JS

This an an AAOS clinical guideline for pediatric distal radial fractures.

This an an AAOS clinical guideline for pediatric distal radial fractures.

Systematic reviews

Rational use of high-flow therapy in infants with bronchiolitis. What do the latest trials tell us?' A Paediatric Research in Emergency Departments International Collaborative perspective.  (2019)

Rational use of high-flow therapy in infants with bronchiolitis. What do the latest trials tell us?' A Paediatric Research in Emergency Departments International Collaborative perspective.

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O'Brien S, Craig S, Babl FE, Borland ML, Oakley E, Dalziel SR; Paediatric Research in Emergency Departments International Collaborative (PREDICT)

O'Brien S, Craig S, Babl FE, Borland ML, Oakley E, Dalziel SR; Paediatric Res...

Over the past decade, the use of high-flow nasal cannulae (HFNC) therapy has increased markedly and it is now utilised not only in the intensive care unit setting but in general paediatric wards and emergency departments. The aim of this systematic review was to summarise and critique the current evidence-base for the use of HFNC in infants with bronchiolitis.

Over the past decade, the use of high-flow nasal cannulae (HFNC) therapy has increased markedly and it is now utilised not only in the intensive care unit setting but in general paediatric wards and emergency departments. The aim of this systematic review was to summarise and critique the current evidence-base for the use of HFNC in infants with bronchiolitis.

Pediatric trauma triage: A Pediatric Trauma Society Research Committee systematic review  (2020)

Pediatric trauma triage: A Pediatric Trauma Society Research Committee systematic review

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Mora MC, Veras L, Burke RV, et al.

Mora MC, Veras L, Burke RV, et al.

This study evaluated existing evidence for pediatric trauma triage. Questions defined a priori were as follows: (1) Do prehospital trauma triage criteria reduce mortality? (2) Do prehospital trauma scoring systems predict outcomes? (3) Do trauma center activation criteria predict outcomes? (4) Do trauma center activation criteria predict need for procedural or operative interventions? (5) Do trauma bay pediatric trauma scoring systems predict outcomes? (6) What secondary triage criteria for transfer of children exist?

This study evaluated existing evidence for pediatric trauma triage. Questions defined a priori were as follows: (1) Do prehospital trauma triage criteria reduce mortality? (2) Do prehospital trauma scoring systems predict outcomes? (3) Do trauma center activation criteria predict outcomes? (4) Do trauma center activation criteria predict need for procedural or operative interventions? (5) Do trauma bay pediatric trauma scoring systems predict outcomes? (6) What secondary triage criteria for transfer of children exist?

Review: Addressing Key Clinical Care and Clinical Research Needs in Severe Pediatric Traumatic Brain Injury: Perspectives From a Focused International Conference.  (2021)

Review: Addressing Key Clinical Care and Clinical Research Needs in Severe Pediatric Traumatic Brain Injury: Perspectives From a Focused International Conference.

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Nacoti M, Fazzi F, Biroli F, Zangari R, Barbui T, Kochanek PM, Collaborative Pediatric TBI Working Group

Nacoti M, Fazzi F, Biroli F, Zangari R, Barbui T, Kochanek PM, Collaborative ...

We explore the clinical and research unmet needs focusing on severe pediatric TBI to identify best practices in pathways of care and optimize both inpatient and outpatient management of children following TBI.

We explore the clinical and research unmet needs focusing on severe pediatric TBI to identify best practices in pathways of care and optimize both inpatient and outpatient management of children following TBI.

Fluid treatment for children with diabetic ketoacidosis: How do the results of the pediatric emergency care applied research network Fluid Therapies Under Investigation in Diabetic Ketoacidosis (FLUID) Trial change our perspective?  (2019)

Fluid treatment for children with diabetic ketoacidosis: How do the results of the pediatric emergency care applied research network Fluid Therapies Under Investigation in Diabetic Ketoacidosis (FLUID) Trial change our perspective?

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Glaser N, Kuppermann N.

Glaser N, Kuppermann N.

The optimal fluid treatment protocol for children with diabetic ketoacidosis (DKA) has long been a subject of controversy. Until recently, there was no high-quality evidence from randomized clinical trials to support an optimal guideline, and recommendations were mainly based on theoretical considerations. As a consequence, fluid treatment protocols for children with DKA vary between institutions (and countries). In June 2018, the results from the Fluid Therapies Under Investigation in DKA Trial conducted in the Pediatric Emergency Care Applied Research Network were published. This large, factorial-designed randomized controlled trial assessed neurological outcomes of 1387 children with DKA who were treated with one of four fluid protocols that varied in infusion rate and sodium content. In this commentary, we review and discuss the results of this new study and the implications for clinical care of DKA in children.

The optimal fluid treatment protocol for children with diabetic ketoacidosis (DKA) has long been a subject of controversy. Until recently, there was no high-quality evidence from randomized clinical trials to support an optimal guideline, and recommendations were mainly based on theoretical considerations. As a consequence, fluid treatment protocols for children with DKA vary between institutions (and countries). In June 2018, the results from the Fluid Therapies Under Investigation in DKA Trial conducted in the Pediatric Emergency Care Applied Research Network were published. This large, factorial-designed randomized controlled trial assessed neurological outcomes of 1387 children with DKA who were treated with one of four fluid protocols that varied in infusion rate and sodium content. In this commentary, we review and discuss the results of this new study and the implications for clinical care of DKA in children.

Key studies

Key Study: Physiologic monitoring practices during pediatric procedural sedation: a report from the Pediatric Sedation Research Consortium  (2012)

Key Study: Physiologic monitoring practices during pediatric procedural sedation: a report from the Pediatric Sedation Research Consortium

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Langhan ML, Mallory M, Hertzog J, Lowrie L, Cravero J

Langhan ML, Mallory M, Hertzog J, Lowrie L, Cravero J

This study aimed to describe the frequency of different physiologic monitoring modalities and combinations of modalities used during pediatric procedural sedation and to describe the variations of monitoring and whether or not sedations meet monitoring guidelines.

This study aimed to describe the frequency of different physiologic monitoring modalities and combinations of modalities used during pediatric procedural sedation and to describe the variations of monitoring and whether or not sedations meet monitoring guidelines.

Key Study: The incidence and nature of adverse events during pediatric sedation/anesthesia with propofol for procedures outside the operating room: a report from the Pediatric Sedation Research Consortium  (2009)

Key Study: The incidence and nature of adverse events during pediatric sedation/anesthesia with propofol for procedures outside the operating room: a report from the Pediatric Sedation Research Consortium

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Cravero JP, Beach ML, Blike GT, Gallagher SM, Hertzog JH,

Cravero JP, Beach ML, Blike GT, Gallagher SM, Hertzog JH,

This study aims to delineate the nature and frequency of adverse events associate with propofol-based sedation/anesthesia care using prospectively collected data on pediatric sedation/anesthesia outside the operating room (OR).

This study aims to delineate the nature and frequency of adverse events associate with propofol-based sedation/anesthesia care using prospectively collected data on pediatric sedation/anesthesia outside the operating room (OR).

Key Study: Incidence and nature of adverse events during pediatric sedation/anesthesia for procedures outside the operating room: report from the Pediatric Sedation Research Consortium  (2006)

Key Study: Incidence and nature of adverse events during pediatric sedation/anesthesia for procedures outside the operating room: report from the Pediatric Sedation Research Consortium

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Cravero JP, Blike GT, Beach M, Gallagher SM, Hertzog JH, Havidich JE, Gelman B

Cravero JP, Blike GT, Beach M, Gallagher SM, Hertzog JH, Havidich JE, Gelman B

The objective of this study was to use a large database of prospectively collected data on pediatric sedation and/or anesthesia for diagnostic and therapeutic procedures to delineate the nature and the frequency of adverse events that are associated with sedation/anesthesia care for procedures that are performed outside the operating room in children.

The objective of this study was to use a large database of prospectively collected data on pediatric sedation and/or anesthesia for diagnostic and therapeutic procedures to delineate the nature and the frequency of adverse events that are associated with sedation/anesthesia care for procedures that are performed outside the operating room in children.

Key Study: Photographing Injuries in the Acute Care Setting: Development and Evaluation of a Standardized Protocol for Research, Forensics, and Clinical Practice  (2016)

Key Study: Photographing Injuries in the Acute Care Setting: Development and Evaluation of a Standardized Protocol for Research, Forensics, and Clinical Practice

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Bloemen EM, Rosen T, Cline Schiroo JA, Clark S, Mulcare MR, Stern ME, Mysliwiec R, Flomenbaum NE, Lachs MS, Hargarten S

Bloemen EM, Rosen T, Cline Schiroo JA, Clark S, Mulcare MR, Stern ME, Mysliwi...

Our goal was to develop and evaluate a protocol for standardized photography of injuries that may be broadly applied.

Our goal was to develop and evaluate a protocol for standardized photography of injuries that may be broadly applied.

Key Study: Major Adverse Events and Relationship to Nil per Os Status in Pediatric Sedation/Anesthesia Outside the Operating Room: A Report of the Pediatric Sedation Research Consortium  (2016)

Key Study: Major Adverse Events and Relationship to Nil per Os Status in Pediatric Sedation/Anesthesia Outside the Operating Room: A Report of the Pediatric Sedation Research Consortium

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Beach ML, Cohen DM, Gallagher SM, Cravero JP

Beach ML, Cohen DM, Gallagher SM, Cravero JP

This study evaluated aspiration episodes and a combined outcome of major adverse events (aspiration, death, cardiac arrest, or unplanned hospital admission) with respect to NPO status, American Society of Anesthesiologists physical status, age, propofol use, procedure types, and urgency of the procedure.

This study evaluated aspiration episodes and a combined outcome of major adverse events (aspiration, death, cardiac arrest, or unplanned hospital admission) with respect to NPO status, American Society of Anesthesiologists physical status, age, propofol use, procedure types, and urgency of the procedure.

Key Study: The Impact of Marijuana Policies on Youth: Clinical, Research, and Legal Update  (2015)

Key Study: The Impact of Marijuana Policies on Youth: Clinical, Research, and Legal Update

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Ammerman, S., Ryan, S., Adelman, W. P., & THE COMMITTEE ON SUBSTANCE ABUSE, T. C. O. A.

Ammerman, S., Ryan, S., Adelman, W. P., & THE COMMITTEE ON SUBSTANCE ABUS...

This technical report updates the 2004 American Academy of Pediatrics technical report on the legalization of marijuana

This technical report updates the 2004 American Academy of Pediatrics technical report on the legalization of marijuana

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Hospital Emergency Treatment of Convulsive Status Epilepticus: Comparison of Pathways From Ten Pediatric Research Centers  (2018)

Hospital Emergency Treatment of Convulsive Status Epilepticus: Comparison of Pathways From Ten Pediatric Research Centers

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We aimed to evaluate and compare the status epilepticus treatment pathways used by pediatric status epilepticus research group (pSERG) hospitals in the United States and the American Epilepsy Society (AES) status epilepticus guideline.

We aimed to evaluate and compare the status epilepticus treatment pathways used by pediatric status epilepticus research group (pSERG) hospitals in the United States and the American Epilepsy Society (AES) status epilepticus guideline.

A research agenda for assessment and management of psychosis in emergency department patients  (2019)

A research agenda for assessment and management of psychosis in emergency department patients

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Peltzer-Jones, J., K. Nordstrom, G. Currier, J. S. Berlin, C. Singh and S. Schneider

Peltzer-Jones, J., K. Nordstrom, G. Currier, J. S. Berlin, C. Singh and S. Sc...

TREKK.ca Info Pages

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Canada Research Chair in Knowledge Synthesis and Translation

Posted: Jul 16, 2019  | Announcement  | Team: News and Events 


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Parents Needed for COVID-19 Study

Posted: Apr 21, 2020  | Announcement  | Team: News and Events 


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Storytelling helping children with croup

Posted: Nov 21, 2013  | Story  | Team: News and Events 


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Sick All Night - A storybook on gastroenteritis

Posted: Oct 17, 2017  | Announcement  | Team: News and Events 


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Gastroenteritis video for parents

Posted: Nov 03, 2016  | Announcement  | Team: News and Events 
Tags: Gastroenteritis


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Gastroenteritis video wins runner-up prize

Posted: Jan 19, 2017  | Announcement  | Team: News and Events 


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Award-winning tools

Posted: Jan 31, 2019  | Announcement  | Team: News and Events 


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VOTING NOW OPEN: Bronchiolitis video for parents

Posted: Nov 05, 2019  | Announcement  | Team: News and Events 


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Profiling pediatric pain expert: Dr. Samina Ali

Posted: Mar 18, 2016  | Announcement  | Team: News and Events 


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Child Health Research Days 2017

Posted: Aug 14, 2017  | Announcement  | Team: News and Events 


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New Chair for the Pediatric Emergency Research Networks

Posted: Jun 02, 2014  | Announcement  | Team: News and Events 


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Reinventing Research: Engaging Patients and Parents

Posted: Jul 14, 2014  | Story  | Team: News and Events 


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Dr. Amy Plint on wrist buckle fractures

Posted: Oct 06, 2015  | Announcement  | Team: News and Events 


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2021 CIHR IHDCYH Talks Video Competition

Posted: Sep 22, 2021  | Announcement  | Team: News and Events 


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Has your child tested positive for COVID-19?

Posted: Jan 26, 2021  | Announcement  | Team: News and Events 


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Emergency Medicine Cases Bronchiolitis Podcast

Posted: Feb 10, 2015  | Announcement  | Team: News and Events 
Tags: Bronchiolitis


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Canadian Anaphylaxis Action Plan for Kids

Posted: Feb 25, 2019  | Announcement  | Team: News and Events 


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TREKK Welcomes New Board Members

Posted: Jun 29, 2021  | Announcement  | Team: News and Events 


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Outstanding Mentor Award

Posted: Nov 03, 2016  | Announcement  | Team: News and Events 


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2017 Annual PERC Scientific Meeting

Posted: Nov 03, 2016  | Announcement  | Team: News and Events 


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New Parent Resource from ECHO

Posted: May 13, 2022  | Announcement  | Team: News and Events 


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I Love to Read Month

Posted: Feb 18, 2020  | Announcement  | Team: News and Events 


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New Board of Directors Member

Posted: Dec 19, 2016  | Announcement  | Team: News and Events 


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News Story: Guidelines for managing child pain in the ED

Posted: Jul 15, 2016  | Announcement  | Team: News and Events 


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Brain Awareness Week

Posted: Mar 11, 2019  | Announcement  | Team: News and Events 


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CBC Radio Active Child Health Series

Posted: Sep 08, 2016  | Announcement  | Team: News and Events 


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Bronchiolitis Bottom Line: Two Year Review

Posted: May 02, 2017  | Announcement  | Team: News and Events 


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Job posting: Project Coordinator

Posted: Mar 09, 2022  | Announcement  | Team: News and Events 


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Congratulations Dr. Samina Ali!

Posted: Nov 19, 2018  | Announcement  | Team: News and Events 


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New asthma video for parents

Posted: Mar 22, 2021  | Announcement  | Team: News and Events 


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New study: Do IV Fluids affect risk of Cerebral Edema in DKA?

Posted: Jun 18, 2018  | Announcement  | Team: News and Events 


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Learning to Live With Chronic Pain

Posted: Apr 11, 2017  | Announcement  | Team: News and Events 


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Podcast: Pediatric Procedural Sedation

Posted: Feb 09, 2016  | Announcement  | Team: News and Events 
Tags: Procedural Sedation, Procedural Pain


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Study Highlight - Publication Bias in Child Health

Posted: Aug 15, 2018  | Announcement  | Team: News and Events 


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Guidelines for Pediatric Concussion Launched in Ottawa

Posted: Jun 26, 2014  | Story  | Team: News and Events 
Tags: Concussion


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Emergency Medicine gets full department status at U of S

Posted: Jul 15, 2016  | Announcement  | Team: News and Events 


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Pediatric Pain Letter

Posted: Nov 21, 2017  | Announcement  | Team: News and Events 


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New PedsPac!

Posted: Jan 31, 2019  | Announcement  | Team: News and Events 


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NEW Parent Tools!

Posted: May 30, 2019  | Announcement  | Team: News and Events 


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TREKK Scholars & Fellows Program

Posted: Jul 05, 2021  | Announcement  | Team: News and Events 


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Parent tools - UTI and Bronchiolitis

Posted: Jan 09, 2020  | Announcement  | Team: News and Events 


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Brain Injury Awareness Month 2019

Posted: Jun 13, 2019  | Announcement  | Team: News and Events 


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Parent tools - CTV Winnipeg

Posted: Jun 18, 2019  | Announcement  | Team: News and Events 


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TREKK Board Announcement

Posted: May 21, 2019  | Announcement  | Team: News and Events 


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Predicting the duration of post-concussion symptoms

Posted: Mar 10, 2016  | Announcement  | Team: News and Events 


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A qualitative ‘TREKK’ across Newfoundland

Posted: Oct 29, 2013  | Blog  | Team: News and Events 
Tags: Research


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Does a child's cough sound like a barking seal? Could be croup

Posted: May 01, 2015  | Announcement  | Team: News and Events 
Tags: Croup, Infection



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