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Sickle Cell Disease (SCD) is a genetic disorder of the hemoglobin, in which sickling of red blood cells results in hemolysis and vaso-occlusion. Newborn screening has led to early identification of SCD in many regions across Canada. While homozygous SCD (HbSS) is the most severe, other sickling syndromes (eg HbSC) may present similarly. Patients with SCD can present with a number of complications.

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Key Resources 

Sickle Cell Disease (SCD) Evidence Repository (2022)

Sickle Cell Disease (SCD) Evidence Repository (2022)

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Dr. Rachel Kesselman and Dr. Jayson Stoffman

Dr. Rachel Kesselman and Dr. Jayson Stoffman

For a list of references that will inform the development of this resource, see Evidence Repository: Sickle Cell Disease (2022).

Bottom Line Recommendations: Sickle Cell Disease (2023)

Bottom Line Recommendations: Sickle Cell Disease (2023)

Download

Dr. Rachel Kesselman and Dr. Jayson Stoffman

Dr. Rachel Kesselman and Dr. Jayson Stoffman

Bottom line recommendations for the treatment of Sickle Cell Disease (SCD).

Recommandations de base: Anémie falciforme (2023)

Recommandations de base: Anémie falciforme (2023)

Download

Dr. Rachel Kesselman and Dr. Jayson Stoffman

Dr. Rachel Kesselman and Dr. Jayson Stoffman

Sickle Cell Disease (SCD) Evidence Repository (2022)

Sickle Cell Disease (SCD) Evidence Repository (2022)

Download

Dr. Rachel Kesselman and Dr. Jayson Stoffman

Dr. Rachel Kesselman and Dr. Jayson Stoffman

For a list of references that will inform the development of this resource, see Evidence Repository: Sickle Cell Disease (2022).

Bottom Line Recommendations: Sickle Cell Disease (2023)

Bottom Line Recommendations: Sickle Cell Disease (2023)

Download

Dr. Rachel Kesselman and Dr. Jayson Stoffman

Dr. Rachel Kesselman and Dr. Jayson Stoffman

Bottom line recommendations for the treatment of Sickle Cell Disease (SCD).

Recommandations de base: Anémie falciforme (2023)

Recommandations de base: Anémie falciforme (2023)

Download

Dr. Rachel Kesselman and Dr. Jayson Stoffman

Dr. Rachel Kesselman and Dr. Jayson Stoffman