Lyme Disease
BROWSE INFORMATION REPOSITORY
Clinical guidelines
Practice parameter: treatment of nervous system Lyme disease (an evidence-based review): report of the Quality Standards Subcommittee of the American Academy of Neurology (2007)
Practice parameter: treatment of nervous system Lyme disease (an evidence-based review): report of the Quality Standards Subcommittee of the American Academy of Neurology
- Visit
Halperin JJ, Shapiro ED, Logigian E, Belman AL, Dotevall L, Wormser GP, Krupp L, Gronseth G, Bever CT Jr; Quality Standards Subcommittee of the American Acad...
Halperin JJ, Shapiro ED, Logigian E, Belman AL, Dotevall L, Wormser GP, Krupp...
Provides evidence-based recommendations on the treatment of nervous system Lyme disease and post-Lyme syndrome. Three questions were addressed: 1) Which antimicrobial agents are effective? 2) Are different regimens preferred for different manifestations of nervous system Lyme disease? 3) What duration of therapy is needed?
The clinical assessment, treatment, and prevention of lyme disease, human granulocytic anaplasmosis, and babesiosis: clinical practice guidelines by the Infectious Diseases Society of America (2006)
The clinical assessment, treatment, and prevention of lyme disease, human granulocytic anaplasmosis, and babesiosis: clinical practice guidelines by the Infectious Diseases Society of America
- Visit
Wormser GP, Dattwyler RJ, Shapiro ED, Halperin JJ, Steere AC, Klempner MS, Krause PJ, Bakken JS, Strle F, Stanek G, Bockenstedt L, Fish D, Dumler JS, Nadelma...
Wormser GP, Dattwyler RJ, Shapiro ED, Halperin JJ, Steere AC, Klempner MS, Kr...
Evidence-based guidelines for the management of patients with Lyme disease, human granulocytic anaplasmosis (formerly known as human granulocytic ehrlichiosis), and babesiosis.
Practice parameter: treatment of nervous system Lyme disease (an evidence-based review): report of the Quality Standards Subcommittee of the American Academy of Neurology (2007)
Practice parameter: treatment of nervous system Lyme disease (an evidence-based review): report of the Quality Standards Subcommittee of the American Academy of Neurology
- Visit
Halperin JJ, Shapiro ED, Logigian E, Belman AL, Dotevall L, Wormser GP, Krupp L, Gronseth G, Bever CT Jr; Quality Standards Subcommittee of the American Acad...
Halperin JJ, Shapiro ED, Logigian E, Belman AL, Dotevall L, Wormser GP, Krupp...
Provides evidence-based recommendations on the treatment of nervous system Lyme disease and post-Lyme syndrome. Three questions were addressed: 1) Which antimicrobial agents are effective? 2) Are different regimens preferred for different manifestations of nervous system Lyme disease? 3) What duration of therapy is needed?
The clinical assessment, treatment, and prevention of lyme disease, human granulocytic anaplasmosis, and babesiosis: clinical practice guidelines by the Infectious Diseases Society of America (2006)
The clinical assessment, treatment, and prevention of lyme disease, human granulocytic anaplasmosis, and babesiosis: clinical practice guidelines by the Infectious Diseases Society of America
- Visit
Wormser GP, Dattwyler RJ, Shapiro ED, Halperin JJ, Steere AC, Klempner MS, Krause PJ, Bakken JS, Strle F, Stanek G, Bockenstedt L, Fish D, Dumler JS, Nadelma...
Wormser GP, Dattwyler RJ, Shapiro ED, Halperin JJ, Steere AC, Klempner MS, Kr...
Evidence-based guidelines for the management of patients with Lyme disease, human granulocytic anaplasmosis (formerly known as human granulocytic ehrlichiosis), and babesiosis.
Summaries of systematic reviews
Cochrane Summary: Treatment for the neurological complications of Lyme disease (2016)
Cochrane Summary: Treatment for the neurological complications of Lyme disease
- Visit
Cadavid D, Auwaerter PG, Rumbaugh J, Gelderblom H
Cadavid D, Auwaerter PG, Rumbaugh J, Gelderblom H
Objective: To assess the effects of antibiotics for the treatment of Lyme neuroborreliosis (LNB).
Cochrane Summary: Treatment for the neurological complications of Lyme disease (2016)
Cochrane Summary: Treatment for the neurological complications of Lyme disease
- Visit
Cadavid D, Auwaerter PG, Rumbaugh J, Gelderblom H
Cadavid D, Auwaerter PG, Rumbaugh J, Gelderblom H
Objective: To assess the effects of antibiotics for the treatment of Lyme neuroborreliosis (LNB).
Systematic reviews
Review: Lyme Disease: Emergency Department Considerations (2017)
Review: Lyme Disease: Emergency Department Considerations
- Visit
Applegren ND, Kraus CK
Applegren ND, Kraus CK
Objective: We sought to review the etiology of LD, describe its clinical presentations and sequela, and provide a practical classification and approach to ED management of patients with LD-related presentations.
Cochrane Systematic Review: Antibiotics for the neurological complications of Lyme disease (2016)
Cochrane Systematic Review: Antibiotics for the neurological complications of Lyme disease
- Visit
Cadavid D, Auwaerter PG, Rumbaugh J, Gelderblom H
Cadavid D, Auwaerter PG, Rumbaugh J, Gelderblom H
Objective: To assess the effects of antibiotics for the treatment of Lyme neuroborreliosis (LNB).
Review: Lyme disease: clinical diagnosis and treatment (2014)
Review: Lyme disease: clinical diagnosis and treatment
- Visit
Hatchette TF, Davis I, Johnston BL
Hatchette TF, Davis I, Johnston BL
Objective: To review the clinical diagnosis and treatment of Lyme disease for front-line clinicians.
Review: Lyme Disease: Emergency Department Considerations (2017)
Review: Lyme Disease: Emergency Department Considerations
- Visit
Applegren ND, Kraus CK
Applegren ND, Kraus CK
Objective: We sought to review the etiology of LD, describe its clinical presentations and sequela, and provide a practical classification and approach to ED management of patients with LD-related presentations.
Cochrane Systematic Review: Antibiotics for the neurological complications of Lyme disease (2016)
Cochrane Systematic Review: Antibiotics for the neurological complications of Lyme disease
- Visit
Cadavid D, Auwaerter PG, Rumbaugh J, Gelderblom H
Cadavid D, Auwaerter PG, Rumbaugh J, Gelderblom H
Objective: To assess the effects of antibiotics for the treatment of Lyme neuroborreliosis (LNB).
Review: Lyme disease: clinical diagnosis and treatment (2014)
Review: Lyme disease: clinical diagnosis and treatment
- Visit
Hatchette TF, Davis I, Johnston BL
Hatchette TF, Davis I, Johnston BL
Objective: To review the clinical diagnosis and treatment of Lyme disease for front-line clinicians.
Key studies
Key study: Validation of a Clinical Prediction Rule to Distinguish Lyme Meningitis From Aseptic Meningitis (2012)
Key study: Validation of a Clinical Prediction Rule to Distinguish Lyme Meningitis From Aseptic Meningitis
- Visit
Cohn KA,Thompson AD,Shah SS,Hines EM,Lyons TW,Welsh EJ,Nigrovic LE
Cohn KA,Thompson AD,Shah SS,Hines EM,Lyons TW,Welsh EJ,Nigrovic LE
Objective: The goal of this study was to test the performance of the Rule of 7's in a multicenter cohort of children with CSF pleocytosis.
Key study: Prospective Validation of a Clinical Prediction Model for Lyme Meningitis in Children (2009)
Key study: Prospective Validation of a Clinical Prediction Model for Lyme Meningitis in Children
- Visit
Garro AC,Rutman M,Simonsen K,Jaeger JL,Chapin K,Lockhart G
Garro AC,Rutman M,Simonsen K,Jaeger JL,Chapin K,Lockhart G
Objective: A clinical prediction model was developed to distinguish Lyme meningitis from other causes of aseptic meningitis. Our objective was to prospectively validate this model.
Key study: Lyme neuroborreliosis in children: a prospective study of clinical features, prognosis, and outcome (2008)
Key study: Lyme neuroborreliosis in children: a prospective study of clinical features, prognosis, and outcome
- Visit
Skogman BH, Croner S, Nordwall M, Eknefelt M, Ernerudh J, Forsberg P
Skogman BH, Croner S, Nordwall M, Eknefelt M, Ernerudh J, Forsberg P
Objective: Evaluation of children with clinically suspected neuroborreliosis (NB) is difficult. With a prospective study design we wanted to characterize children with signs and symptoms indicative for NB, investigate clinical outcome and, if possible, identify factors of importance for recovery.
Key study: Prediction of Lyme Meningitis in Children From a Lyme DiseaseEndemic Region: A Logistic-Regression Model Using History, Physical, and Laboratory Findings (2006)
Key study: Prediction of Lyme Meningitis in Children From a Lyme DiseaseEndemic Region: A Logistic-Regression Model Using History, Physical, and Laboratory Findings
- Visit
Avery RA, Frank G, Glutting JJ, Eppes SC
Avery RA, Frank G, Glutting JJ, Eppes SC
Objective: To create a statistical model to predict LM versus AM in children based on history, physical, and laboratory findings during the initial presentation of meningitis.
Key study: Characterization of Lyme Meningitis and Comparison With Viral Meningitis in Children (1999)
Key study: Characterization of Lyme Meningitis and Comparison With Viral Meningitis in Children
- Visit
Eppes SC,Nelson DK,Lewis LL,Klein JD
Eppes SC,Nelson DK,Lewis LL,Klein JD
Objective: The objectives of this study were to characterize Lyme meningitis (LM) in the pediatric population; to compare LM with viral meningitis (VM) with respect to epidemiology, history and physical examination, and laboratory data; and to provide means of early distinction of Lyme neuroborreliosis from other forms of aseptic meningitis.
Key study: Validation of a Clinical Prediction Rule to Distinguish Lyme Meningitis From Aseptic Meningitis (2012)
Key study: Validation of a Clinical Prediction Rule to Distinguish Lyme Meningitis From Aseptic Meningitis
- Visit
Cohn KA,Thompson AD,Shah SS,Hines EM,Lyons TW,Welsh EJ,Nigrovic LE
Cohn KA,Thompson AD,Shah SS,Hines EM,Lyons TW,Welsh EJ,Nigrovic LE
Objective: The goal of this study was to test the performance of the Rule of 7's in a multicenter cohort of children with CSF pleocytosis.
Key study: Prospective Validation of a Clinical Prediction Model for Lyme Meningitis in Children (2009)
Key study: Prospective Validation of a Clinical Prediction Model for Lyme Meningitis in Children
- Visit
Garro AC,Rutman M,Simonsen K,Jaeger JL,Chapin K,Lockhart G
Garro AC,Rutman M,Simonsen K,Jaeger JL,Chapin K,Lockhart G
Objective: A clinical prediction model was developed to distinguish Lyme meningitis from other causes of aseptic meningitis. Our objective was to prospectively validate this model.
Key study: Lyme neuroborreliosis in children: a prospective study of clinical features, prognosis, and outcome (2008)
Key study: Lyme neuroborreliosis in children: a prospective study of clinical features, prognosis, and outcome
- Visit
Skogman BH, Croner S, Nordwall M, Eknefelt M, Ernerudh J, Forsberg P
Skogman BH, Croner S, Nordwall M, Eknefelt M, Ernerudh J, Forsberg P
Objective: Evaluation of children with clinically suspected neuroborreliosis (NB) is difficult. With a prospective study design we wanted to characterize children with signs and symptoms indicative for NB, investigate clinical outcome and, if possible, identify factors of importance for recovery.
Key study: Prediction of Lyme Meningitis in Children From a Lyme DiseaseEndemic Region: A Logistic-Regression Model Using History, Physical, and Laboratory Findings (2006)
Key study: Prediction of Lyme Meningitis in Children From a Lyme DiseaseEndemic Region: A Logistic-Regression Model Using History, Physical, and Laboratory Findings
- Visit
Avery RA, Frank G, Glutting JJ, Eppes SC
Avery RA, Frank G, Glutting JJ, Eppes SC
Objective: To create a statistical model to predict LM versus AM in children based on history, physical, and laboratory findings during the initial presentation of meningitis.
Key study: Characterization of Lyme Meningitis and Comparison With Viral Meningitis in Children (1999)
Key study: Characterization of Lyme Meningitis and Comparison With Viral Meningitis in Children
- Visit
Eppes SC,Nelson DK,Lewis LL,Klein JD
Eppes SC,Nelson DK,Lewis LL,Klein JD
Objective: The objectives of this study were to characterize Lyme meningitis (LM) in the pediatric population; to compare LM with viral meningitis (VM) with respect to epidemiology, history and physical examination, and laboratory data; and to provide means of early distinction of Lyme neuroborreliosis from other forms of aseptic meningitis.
