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Croup is a common respiratory illness caused by a viral infection in the airway. Accompanied by a barky cough and respiratory distress, this illness is most common in children aged birth to 6 years, peaking at 2 years of age.

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Summaries of systematic reviews 

Cochrane Summary: Glucocorticoids for croup in children  (2018)

Cochrane Summary: Glucocorticoids for croup in children

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Gates A, Gates M, Vandermeer B, Johnson C, Hartling L, Johnson DW, Klassen TP,

Gates A, Gates M, Vandermeer B, Johnson C, Hartling L, Johnson DW, Klassen TP,

Objective: To examine the effects of glucocorticoids for the treatment of croup in children aged 0 to 18 years.

Cochrane Summary: Helium-oxygen (heliox) treatment for children with croup  (2018)

Cochrane Summary: Helium-oxygen (heliox) treatment for children with croup

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Moraa I, Sturman N, McGuire TM, van Driel ML,

Moraa I, Sturman N, McGuire TM, van Driel ML,

Objective: To examine the effect of heliox compared to oxygen or other active interventions, placebo, or no treatment, on relieving signs and symptoms in children with croup as determined by a croup score and rates of admission and intubation.

Summary: Evidence for Clinicians: Nebulized epinephrine for croup in children  (2015)

Summary: Evidence for Clinicians: Nebulized epinephrine for croup in children

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Kawaguchi A, Joffe A,

Kawaguchi A, Joffe A,

Expert commentary on the Cochrane Review on nebulized epinephrine for reducing symptoms in children with severe croup. 

Cochrane Summary: Nebulized epinephrine for croup in children  (2013)

Cochrane Summary: Nebulized epinephrine for croup in children

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Bjornson, C, Russell, K, Vandermeer, B, Klassen, TP, Johnson, DW,

Bjornson, C, Russell, K, Vandermeer, B, Klassen, TP, Johnson, DW,

Objective: To assess the efficacy (measured by croup scores, rate of intubation and health care utilization such as rate of hospitalization) and safety (frequency and severity of side effects) of nebulized epinephrine versus placebo in children with croup, evaluated in an emergency department (ED) or hospital setting.

Cochrane Summary: Glucocorticoids for croup in children  (2018)

Cochrane Summary: Glucocorticoids for croup in children

Visit

Gates A, Gates M, Vandermeer B, Johnson C, Hartling L, Johnson DW, Klassen TP,

Gates A, Gates M, Vandermeer B, Johnson C, Hartling L, Johnson DW, Klassen TP,

Objective: To examine the effects of glucocorticoids for the treatment of croup in children aged 0 to 18 years.

Cochrane Summary: Helium-oxygen (heliox) treatment for children with croup  (2018)

Cochrane Summary: Helium-oxygen (heliox) treatment for children with croup

Visit

Moraa I, Sturman N, McGuire TM, van Driel ML,

Moraa I, Sturman N, McGuire TM, van Driel ML,

Objective: To examine the effect of heliox compared to oxygen or other active interventions, placebo, or no treatment, on relieving signs and symptoms in children with croup as determined by a croup score and rates of admission and intubation.

Summary: Evidence for Clinicians: Nebulized epinephrine for croup in children  (2015)

Summary: Evidence for Clinicians: Nebulized epinephrine for croup in children

Visit

Kawaguchi A, Joffe A,

Kawaguchi A, Joffe A,

Expert commentary on the Cochrane Review on nebulized epinephrine for reducing symptoms in children with severe croup. 

Cochrane Summary: Nebulized epinephrine for croup in children  (2013)

Cochrane Summary: Nebulized epinephrine for croup in children

Visit

Bjornson, C, Russell, K, Vandermeer, B, Klassen, TP, Johnson, DW,

Bjornson, C, Russell, K, Vandermeer, B, Klassen, TP, Johnson, DW,

Objective: To assess the efficacy (measured by croup scores, rate of intubation and health care utilization such as rate of hospitalization) and safety (frequency and severity of side effects) of nebulized epinephrine versus placebo in children with croup, evaluated in an emergency department (ED) or hospital setting.

Overviews of systematic reviews 

Cochrane Overview: Evidence Summary: Croup  (2014)

Cochrane Overview: Evidence Summary: Croup

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Alberta Research Centre for Health Evidence (ARCHE),

Alberta Research Centre for Health Evidence (ARCHE),

The purpose of this document is to describe the effectiveness of four treatment options, based on a 2012 Overview of Reviews.

Cochrane Overview: The Cochrane Library and the treatment of croup in children: an overview of reviews  (2010)

Cochrane Overview: The Cochrane Library and the treatment of croup in children: an overview of reviews

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Bjornson, C, Russell, K, Foisy, M, Johnson, D,

Bjornson, C, Russell, K, Foisy, M, Johnson, D,

Objective: To synthesize the evidence currently in the Cochrane Database of Systematic Reviews (CDSR) related to the clinical effectiveness and applicability of four treatments for croup - glucocorticoids, epinephrine, heliox and humidified air.

Cochrane Overview: Evidence Summary: Croup  (2014)

Cochrane Overview: Evidence Summary: Croup

Download

Alberta Research Centre for Health Evidence (ARCHE),

Alberta Research Centre for Health Evidence (ARCHE),

The purpose of this document is to describe the effectiveness of four treatment options, based on a 2012 Overview of Reviews.

Cochrane Overview: The Cochrane Library and the treatment of croup in children: an overview of reviews  (2010)

Cochrane Overview: The Cochrane Library and the treatment of croup in children: an overview of reviews

Visit

Bjornson, C, Russell, K, Foisy, M, Johnson, D,

Bjornson, C, Russell, K, Foisy, M, Johnson, D,

Objective: To synthesize the evidence currently in the Cochrane Database of Systematic Reviews (CDSR) related to the clinical effectiveness and applicability of four treatments for croup - glucocorticoids, epinephrine, heliox and humidified air.


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