Pseudomonas Infections Cochrane Pediatric Emergency Medicine Reviews

Browse Cochrane Pediatric Emergency Medicine Reviews


Cochrane Systematic Review: Once-daily versus multiple-daily dosing with intravenous aminoglycosides for cystic fibrosis


Smyth AR, Bhatt J

OBJECTIVES: To assess the effectiveness and safety of once-daily versus multiple-daily dosing of intravenous aminoglycoside antibiotics for the management of pulmonary exacerbations in cystic fibrosis.

Cochrane Systematic Review: Macrolide antibiotics for cystic fibrosis


Southern KW, Barker PM, Solis-Moya A, Patel L

OBJECTIVES: To test the hypotheses that, in people with cystic fibrosis, macrolide antibiotics: 1. improve clinical status compared to placebo or another antibiotic; 2. do not have unacceptable adverse effects. If benefit was demonstrated, we aimed to assess the optimal type, dose and duration of macrolide therapy.

Cochrane Systematic Review: Oral anti-pseudomonal antibiotics for cystic fibrosis


Remmington T, Jahnke N, Harkensee C

OBJECTIVES: To determine the benefit or harm of oral anti-pseudomonal antibiotic therapy for people with CF, colonised with Pseudomonas aeruginosa, in the:1. treatment of a pulmonary exacerbation; and 2. long-term treatment of chronic infection.

Cochrane Systematic Review: Inhaled antibiotics for pulmonary exacerbations in cystic fibrosis


Ryan G, Jahnke N, Remmington T

OBJECTIVES: To determine if treatment of pulmonary exacerbations with inhaled antibiotics in people with cystic fibrosis improves their quality of life, reduces time off school or work and improves their long-term survival.