Prenatal Exposure Delayed Effects Cochrane Pediatric Emergency Medicine Reviews

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Cochrane Systematic Review: Common antiepileptic drugs in pregnancy in women with epilepsy


Adab N, Tudur SC, Vinten J, Williamson P, Winterbottom J

OBJECTIVES: To assess the adverse effects of commonly used antiepileptic drugs on maternal and fetal outcomes in pregnancy in women with epilepsy. Comparison of outcomes following specific antiepileptic drug exposures in utero to unexposed pregnancies in the general population or women with epilepsy are described. The current manuscript reports the first phase of this review which focuses upon neurodevelopmental outcomes in children exposed to antiepileptic drugs in utero.