Trauma is the leading cause of morbidity and mortality in children. Children have unique injury patterns and substantial differences in their response to trauma when compared with adults; this requires special consideration when addressing the assessment and management of pediatric trauma.
Cochrane Systematic Review: Hyperventilation therapy for acute traumatic brain injury
Schierhout G, Roberts I
Schierhout G, Roberts I
OBJECTIVES: To quantify the effect of hyperventilation on death and neurological disability following head injury.
OBJECTIVES: To quantify the effect of hyperventilation on death and neurological disability following head injury.
Cochrane Systematic Review: Decompressive craniectomy for the treatment of refractory high intracranial pressure in traumatic brain injury
Sahuquillo J, Arikan F
Sahuquillo J, Arikan F
OBJECTIVES: To assess the effects of secondary decompressive craniectomy (DC) on outcome and quality of life in patients with severe TBI in whom conventional medical therapeutic measures have failed to control raised ICP.
OBJECTIVES: To assess the effects of secondary decompressive craniectomy (DC) on outcome and quality of life in patients with severe TBI in whom conventional medical therapeutic measures have failed to control raised ICP.
Cochrane Systematic Review: Antifibrinolytic drugs for acute traumatic injury
Roberts I, Shakur H, Ker K, Coats T; CRASH-2 Trial collaborators
Roberts I, Shakur H, Ker K, Coats T; CRASH-2 Trial collaborators
OBJECTIVES: To quantify the effects of antifibrinolytic drugs on mortality, vascular occlusive events, surgical intervention and receipt of blood transfusion after acute traumatic injury.
OBJECTIVES: To quantify the effects of antifibrinolytic drugs on mortality, vascular occlusive events, surgical intervention and receipt of blood transfusion after acute traumatic injury.
Cochrane Systematic Review: Bradykinin beta-2 receptor antagonists for acute traumatic brain injury
Ker K, Blackhall K
Ker K, Blackhall K
OBJECTIVES: The objective was to assess the safety and effectiveness of beta-2 receptor antagonists for TBI.
OBJECTIVES: The objective was to assess the safety and effectiveness of beta-2 receptor antagonists for TBI.
Cochrane Systematic Review: Thromboprophylaxis for trauma patients
Barrera LM, Perel P, Ker K, Cirocchi R, Farinella E, Morales Uribe CH
Barrera LM, Perel P, Ker K, Cirocchi R, Farinella E, Morales Uribe CH
OBJECTIVES: To assess the effects of thromboprophylaxis in trauma patients on mortality and incidence of deep vein thrombosis and pulmonary embolism. To compare the effects of different thromboprophylaxis interventions and their effects according to the type of trauma.
OBJECTIVES: To assess the effects of thromboprophylaxis in trauma patients on mortality and incidence of deep vein thrombosis and pulmonary embolism. To compare the effects of different thromboprophylaxis interventions and their effects according to the type of trauma.
Cochrane Systematic Review: Progesterone for acute traumatic brain injury
Ma J, Huang S, Qin S, You C
Ma J, Huang S, Qin S, You C
OBJECTIVES: To assess the effectiveness and safety of progesterone in people with acute TBI.
OBJECTIVES: To assess the effectiveness and safety of progesterone in people with acute TBI.
Cochrane Systematic Review: Primary closure versus delayed closure for non bite traumatic wounds within 24 hours post injury
Eliya-Masamba MC, Banda GW
Eliya-Masamba MC, Banda GW
OBJECTIVES: To determine the effect on time to healing of primary closure versus delayed closure for non bite traumatic wounds presenting within 24 hours post injury. To explore the adverse effects of primary closure compared with delayed closure for non bite traumatic wounds presenting within 24 hours post injury.
OBJECTIVES: To determine the effect on time to healing of primary closure versus delayed closure for non bite traumatic wounds presenting within 24 hours post injury. To explore the adverse effects of primary closure compared with delayed closure for non bite traumatic wounds presenting within 24 hours post injury.
Cochrane Systematic Review: Hyperventilation therapy for acute traumatic brain injury
Schierhout G, Roberts I
Schierhout G, Roberts I
OBJECTIVES: To quantify the effect of hyperventilation on death and neurological disability following head injury.
OBJECTIVES: To quantify the effect of hyperventilation on death and neurological disability following head injury.
Cochrane Systematic Review: Decompressive craniectomy for the treatment of refractory high intracranial pressure in traumatic brain injury
Sahuquillo J, Arikan F
Sahuquillo J, Arikan F
OBJECTIVES: To assess the effects of secondary decompressive craniectomy (DC) on outcome and quality of life in patients with severe TBI in whom conventional medical therapeutic measures have failed to control raised ICP.
OBJECTIVES: To assess the effects of secondary decompressive craniectomy (DC) on outcome and quality of life in patients with severe TBI in whom conventional medical therapeutic measures have failed to control raised ICP.
Cochrane Systematic Review: Antifibrinolytic drugs for acute traumatic injury
Roberts I, Shakur H, Ker K, Coats T; CRASH-2 Trial collaborators
Roberts I, Shakur H, Ker K, Coats T; CRASH-2 Trial collaborators
OBJECTIVES: To quantify the effects of antifibrinolytic drugs on mortality, vascular occlusive events, surgical intervention and receipt of blood transfusion after acute traumatic injury.
OBJECTIVES: To quantify the effects of antifibrinolytic drugs on mortality, vascular occlusive events, surgical intervention and receipt of blood transfusion after acute traumatic injury.
Cochrane Systematic Review: Bradykinin beta-2 receptor antagonists for acute traumatic brain injury
Ker K, Blackhall K
Ker K, Blackhall K
OBJECTIVES: The objective was to assess the safety and effectiveness of beta-2 receptor antagonists for TBI.
OBJECTIVES: The objective was to assess the safety and effectiveness of beta-2 receptor antagonists for TBI.
Cochrane Systematic Review: Thromboprophylaxis for trauma patients
Barrera LM, Perel P, Ker K, Cirocchi R, Farinella E, Morales Uribe CH
Barrera LM, Perel P, Ker K, Cirocchi R, Farinella E, Morales Uribe CH
OBJECTIVES: To assess the effects of thromboprophylaxis in trauma patients on mortality and incidence of deep vein thrombosis and pulmonary embolism. To compare the effects of different thromboprophylaxis interventions and their effects according to the type of trauma.
OBJECTIVES: To assess the effects of thromboprophylaxis in trauma patients on mortality and incidence of deep vein thrombosis and pulmonary embolism. To compare the effects of different thromboprophylaxis interventions and their effects according to the type of trauma.
Cochrane Systematic Review: Progesterone for acute traumatic brain injury
Ma J, Huang S, Qin S, You C
Ma J, Huang S, Qin S, You C
OBJECTIVES: To assess the effectiveness and safety of progesterone in people with acute TBI.
OBJECTIVES: To assess the effectiveness and safety of progesterone in people with acute TBI.
Cochrane Systematic Review: Primary closure versus delayed closure for non bite traumatic wounds within 24 hours post injury
Eliya-Masamba MC, Banda GW
Eliya-Masamba MC, Banda GW
OBJECTIVES: To determine the effect on time to healing of primary closure versus delayed closure for non bite traumatic wounds presenting within 24 hours post injury. To explore the adverse effects of primary closure compared with delayed closure for non bite traumatic wounds presenting within 24 hours post injury.
OBJECTIVES: To determine the effect on time to healing of primary closure versus delayed closure for non bite traumatic wounds presenting within 24 hours post injury. To explore the adverse effects of primary closure compared with delayed closure for non bite traumatic wounds presenting within 24 hours post injury.