Common Cold Cochrane Pediatric Emergency Medicine Reviews

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Cochrane Systematic Review: Antibiotics for the common cold and acute purulent rhinitis


Kenealy T, Arroll B

OBJECTIVES: To determine the efficacy of antibiotics compared with placebo for reducing general and specific nasopharyngeal symptoms of acute upper respiratory tract infections (URTIs) (common colds). To determine if antibiotics have any influence on the tcomes for acute purulent rhinitis and acute clear rhinitis lasting less than 10 days before the intervention. To determine whether there are significant adverse outcomes associated with antibiotic therapy for participants with a clinical diagnosis of acute URTI or acute purulent rhinitis.

Cochrane Systematic Review: Antihistamines for the common cold


De Sutter AI, Lemiengre M, Campbell H

OBJECTIVES: To assess in patients with a common cold the effects of antihistamines in alleviating nasal symptoms, or the shortening the duration of illness.

Cochrane Systematic Review: Chinese medicinal herbs for the common cold


Wu T, Zhang J, Qiu Y, Xie L, Liu GJ

OBJECTIVES: To assess the effectiveness and safety of Chinese herbal medicines for the common cold.

Cochrane Systematic Review: Corticosteroids for the common cold


Hayward G, Thompson MJ, Perera R, Del Mar CB, Glasziou PP, Heneghan CJ.

Objectives: To compare corticosteroids versus usual care for the common cold on clinical response rates in children and adults.

Cochrane Systematic Review: Delayed antibiotics for respiratory infections


Spurling GK, Del Mar CB, Dooley L, Foxlee R, Farley R.

Objectives: To evaluate the use of delayed antibiotics compared to immediate or no antibiotics as a prescribing strategy for ARTIs. We evaluated clinical outcomes including duration and severity measures for pain, malaise, fever, cough and rhinorrhoea in sore throat, otitis media, bronchitis (cough) and the common cold. We also evaluated the outcomes of antibiotic use, patient satisfaction, antibiotic resistance and re-consultation rates and use of alternative therapies.

Cochrane Systematic Review: Echinacea for preventing and treating the common cold


Karsch-Vlk M, Barrett B, Kiefer D, Bauer R, Ardjomand-Woelkart K, Linde K.

Objectives: To assess whether there is evidence that Echinacea preparations are effective and safe compared to placebo in the prevention and treatment of the common cold.

Cochrane Systematic Review: Garlic for the common cold


Lissiman E, Bhasale AL, Cohen M.

Objectives: To determine whether garlic (allium sativum) is effective for either the prevention or treatment of the common cold, when compared to placebo, no treatment or other treatments.

Cochrane Systematic Review: Heated, humidified air for the common cold


Singh M, Singh M.

Objectives: To assess the effects of inhaling heated water vapour (steam) in the treatment of the common cold by comparing symptoms, viral shedding and nasal resistance.

Cochrane Systematic Review: Intranasal ipratropium bromide for the common cold


AlBalawi ZH, Othman SS, Alfaleh K.

Objectives: To determine the effect of IB versus placebo or no treatment on severity of rhinorrhoea and nasal congestion in children and adults with the common cold. Subjective overall improvement was another primary outcome and side effects (for example, dry mucous membranes, epistaxis and systemic anticholinergic effects) were reported as a secondary outcome.

Cochrane Systematic Review: Nasal decongestants for the common cold


Taverner D, Latte GJ.

Objectives: To assess the efficacy of nasal decongestants at reducing the symptom of nasal congestion in adults and children with the common cold and to identify possible adverse effects associated with their use.

Cochrane Systematic Review: Non-steroidal anti-inflammatory drugs for the common cold


Kim SY, Chang YJ, Cho HM, Hwang YW, Moon YS.

Objectives: To determine the effects of NSAIDs versus placebo (and other treatments) on signs and symptoms of the common cold, and to determine any adverse effects of NSAIDs in people with the common cold.

Cochrane Systematic Review: Oral antihistamine-decongestant-analgesic combinations for the common cold


De Sutter AI, van Driel ML, Kumar AA, Lesslar O, Skrt A.

Objectives: To assess the effectiveness of antihistamine-decongestant-analgesic combinations in reducing the duration and alleviating the symptoms of the common cold in adults and children.

Cochrane Systematic Review: Saline nasal irrigation for acute upper respiratory tract infections


Kassel JC, King D, Spurling GK.

Objectives: To evaluate the efficacy of saline nasal irrigation in treating the symptoms of acute URTIs.

Cochrane Systematic Review: Vitamin C for preventing and treating the common cold


Hemil H, Chalker E.

Objectives: To find out whether vitamin C reduces the incidence, the duration or severity of the common cold when used either as a continuous regular supplementation every day or as a therapy at the onset of cold symptoms.

Cochrane Systematic Review: Zinc for the common cold


Singh M, Das RR.

Objectives: To assess whether zinc (irrespective of the zinc salt or formulation used) is efficacious in reducing the incidence, severity and duration of common cold symptoms. In addition, we aimed to identify potential sources of heterogeneity in results obtained and to assess their clinical significance.