Bronchiolitis Cochrane Pediatric Emergency Medicine Reviews

Bronchiolitis is a common viral illness. It is most commonly caused by respiratory syncytial virus and typically occurs over the late fall and winter months. Children less than 2 years of age are most commonly affected, with the largest burden of illness being in children less than 12 months of age.

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Cochrane Systematic Review: Antibiotics for bronchiolitis in children


Spurling GK, Doust J, Del Mar CB, Eriksson L

OBJECTIVES: To evaluate the effectiveness of antibiotics for bronchiolitis.

Cochrane Systematic Review: Bronchodilators for bronchiolitis


Gadomski AM, Scribani MB

OBJECTIVES: To assess the effects of bronchodilators on clinical outcomes in infants (0 to 12 months) with acute bronchiolitis.

Cochrane Systematic Review: Chest physiotherapy for acute bronchiolitis in paediatric patients between 0 and 24 months old


Roqu i Figuls M, Gin-Garriga M, Granados Rugeles C, Perrotta C

OBJECTIVES: The main objective was to determine the efficacy of chest physiotherapy in infants aged less than 24 months old with acute bronchiolitis. A condary objective was to determine the efficacy of different techniques of chest physiotherapy (for ample, vibration and percussion and passive forced exhalation).

Cochrane Systematic Review: Epinephrine for bronchiolitis


Hartling L, Bialy LM, Vandermeer B, Tjosvold L, Johnson DW, Plint AC, Klassen...

Objectives: To examine the efficacy and safety of epinephrine in children less than two with viral bronchiolitis.

Cochrane Systematic Review: Heliox inhalation therapy for bronchiolitis in infants


Liet JM, Ducruet T, Gupta V, Cambonie G.

Objectives: To assess heliox in addition to standard medical care for acute bronchiolitis in infants.

Cochrane Systematic Review: Inhaled corticosteroids during acute bronchiolitis in the prevention of post-bronchiolitic wheezing


Blom DJ, Ermers M, Bont L, van Woensel JB, Van Aalderen WM.

Objectives: The objective of this review was to evaluate the effect of inhaled corticosteroids, started during the acute phase of bronchiolitis, on the prevention of post-bronchiolitic wheezing.

Cochrane Systematic Review: Nebulised hypertonic saline solution for acute bronchiolitis in infants


Zhang L, Mendoza-Sassi RA, Wainwright C, Klassen TP.

Objectives: To assess the effects of nebulised hypertonic ( 3%) saline solution in infants with viral bronchiolitis.

Cochrane Systematic Review: Oxygen therapy for lower respiratory tract infections in children between 3 months and 15 years of age


Rojas MX, Granados Rugeles C, Charry-Anzola LP.

Objectives: To determine in the treatment of LRTIs: the effectiveness of oxygen therapy and oxygen delivery methods; the safety of these methods; and indications for oxygen therapy.

Cochrane Systematic Review: Steam inhalation or humidified oxygen for acute bronchiolitis in children up to three years of age


Umoren R, Odey F, Meremikwu MM.

Objectives: To evaluate the effect of steam inhalation or humidified oxygen to relieve respiratory distress and to evaluate adverse events in children up to three years old with acute bronchiolitis.

Cochrane Systematic Review: Surfactant therapy for bronchiolitis in critically ill infants


Ventre K, Haroon M, Davison C.

Objectives: To assess the efficacy of exogenous surfactant for the treatment of bronchiolitis in mechanically ventilated infants and children.

Cochrane Systematic Review: Antibiotics for persistent cough or wheeze following acute bronchiolitis in children


McCallum GB, Morris PS, Chang AB.

Objectives: To determine the effectiveness of antibiotics compared to a control (no treatment or placebo) for persistent respiratory symptoms (within six months), following acute bronchiolitis.