Tran DL, Sintusek P. Efficacy and palatability of the developed polyethylene glycol-based formula for the treatment of children with functional constipation. World J Clin Pediatr. 2025;14(4):108854.
Keihanian F, Maleknejad S, Saeidinia A, Soltanipour S, Pirooz A. Comparison of Ziziphus jujube Mill. Syrup versus polyethylene glycol in children with functional constipation: a randomized clinical trial. Sci Rep. 2025;15(1):1674.
Malekiantaghi A, Miladi M, Shabani Mirzaee H, Tolou Ostadan Yazd M, Eftekhari K. Abdominal massage as an adjunctive therapy for pediatric functional constipation: a randomized controlled trial. Turk J Pediatr. 2025;67(5):669–77.
Bai X, Li D, Tian Y, et al. Effects of Chinese pediatric therapeutic massage on the management of functional constipation in children: A randomized single blind trial. Medicine (Baltimore). 2025;104(52):e46865.
Vadlapudi SS, Poddar U, Srivastava A, Sarma MS. Efficacy of Home-Based Versus Hospital-Based Disimpaction with Polyethylene Glycol in Pediatric Functional Constipation: A Randomized Control Study. Dig Dis Sci. 2025;70(8):2750–9.
Di Lorenzo C, Nurko S, Hyams JS, et al. Randomized controlled trial of linaclotide in children aged 6-17 years with functional constipation. J Pediatr Gastroenterol Nutr. 2024;78(5):1059–68.
Di Lorenzo C, Robert J, Rodriguez-Araujo G, Shakhnovich V, Xie W, Nurko S, et al. Safety and efficacy of linaclotide in children aged 2-5 years with functional constipation: Phase 2, randomized study. J Pediatr Gastroenterol Nutr. 2024;79(3):510–8.
Elkaragy ES, Shamseya MM, Metwally RH, Mansour ER, Lashen SA. Efficacy of lubiprostone for functional constipation treatment in adolescents and children: Randomized controlled trial. J Pediatr Gastroenterol Nutr. 2024;78(4):800–9.
Ansari Chaharsoghi N, Davoodi M, Reihani H, et al. A Comparison of the Effect of Kegel Exercises and Conventional Therapy versus Conventional Therapy Alone in the Treatment of Functional Constipation in Children: A Randomized Clinical Trial. Iran J Med Sci. 2024;49(5):286–93.
Gu X, Yang Z, Kou Y, et al. Effects of Retrograde Colonic Enema-Based Fecal Microbiota Transplantation in the Treatment of Childhood Constipation: A Randomized, Double-Blind, Controlled Trial. Am J Gastroenterol. 2024;119(11):2288–97.
Heemskerk SCM, Dirksen CD, van Kuijk SMJ, et al. Sacral Neuromodulation Versus Conservative Treatment for Refractory Idiopathic Slow-transit Constipation: The Randomized Clinical No.2-Trial. Ann Surg. 2024;279(5):746–54.
Yu ZT, Song JM, Qiao L, et al. A Randomized, Double-Blind, Controlled Trial of Percutaneous Tibial Nerve Stimulation With Pelvic Floor Exercises in the Treatment of Childhood Constipation. Am J Gastroenterol. 2023;118(3):553–60.
Lojanatorn P, Phrommas J, Tanpowpong P, Getsuwan S, Lertudomphonwanit C, Treepongkaruna S. Efficacy of Bacillus clausii in Pediatric Functional Constipation: A Pilot of a Randomized, Double-Blind, Placebo-Controlled Trial. Indian Pediatr. 2023;60(6):453–8.
Anwar Ul Haq MM, Lyons H, Halim M. Pediatric abdominal x-rays in the acute care setting – are we overdiagnosing constipation? Cureus. 2020;12(3):e7283.
Jarzebicka D, Sieczkowska-Golub J, Kierkus J, et al. Peg 3350 versus lactulose for treatment of functional constipation in children: Randomized study. J Pediatr Gastroenterol Nutr. 2019;68(3):318-24.
Dehghani SM, Bahroloolomifard MS, Yousefi G, et al. A randomized controlled double blinded trial to evaluate efficacy of oral administration of black strap molasses (sugarcane extract) in comparison with polyethylene glycol on pediatric functional constipation. J Ethnopharmacol. 2019;238:111845.
Benninga MA, MENA Infant Constipation Study Group, Vandenplas Y. The magnesium-rich formula for functional constipation in infants: A randomized comparator-controlled study. Pediatr Gastroenterol Hepatol Nutr. 2019;22(3):270-81.
Modin L, Walsted AM, Dalby K, Jakobsen MS. Polyethylene glycol maintenance treatment for childhood functional constipation: A randomized, placebo-controlled trial. J Pediatr Gastroenterol Nutr. 2018;67(6):732-7.
van Engelenburg-van Lonkhuyzen ML, Bols EM, Benninga MA, Verwijs WA, de Bie RA. Effectiveness of pelvic physiotherapy in children with functional constipation compared with standard medical care. Gastroenterology. 2017;152(1):82-91.
Freedman SB, Rodean J, Hall M, et al. Delayed diagnoses in children with constipation: Multicenter retrospective cohort study. J Pediatr. 2017;186:87-94.e16.
Shaikh N, Hoberman A, Keren R, et al. Recurrent urinary tract infections in children with bladder and bowel dysfunction. Pediatrics. 2016;137(1):e20152982.
Ormarsson OT, Asgrimsdottir GM, Loftsson T, Stefansson E, Lung SH, Bjornsson ES. Free fatty acid suppositories are as effective as docusate sodium and sorbitol enemas in treating constipation in children. Acta Paediatr. 2016;105(6):689-94.
Modin L, Walsted AM, Rittig CS, Hansen AV, Jakobsen MS. Follow-up in childhood functional constipation: A randomized, controlled clinical trial. J Pediatr Gastroenterol Nutr. 2016;62(4):594-9.
Vilke GM, DeMers G, Patel N, Castillo EM. Safety and efficacy of milk and molasses enemas in the emergency department. J Emerg Med. 2015;48(6):667-70.
Jordan-Ely J, Hutson JM, Southwell BR. Disimpaction of children with severe constipation in 3-4 days in a suburban clinic using polyethylene glycol with electrolytes and sodium picosulphate. J Paediatr Child Health. 2015;51(12):1195-8.
Boles EE, Gaines CL, Tillman EM. Comparison of polyethylene glycol-electrolyte solution vs polyethylene glycol-3350 for the treatment of fecal impaction in pediatric patients. J Pediatr Pharmacol Ther. 2015;20(3):210-6.
Freedman SB, Thull-Freedman J, Rumantir M, Eltorki M, Schuh S. Pediatric constipation in the emergency department: Evaluation, treatment, and outcomes. J Pediatr Gastroenterol Nutr. 2014;59(3):327-33.
Freedman SB, Thull-Freedman J, Manson D, et al. Pediatric abdominal radiograph use, constipation, and significant misdiagnoses. J Pediatr. 2014;164(1):83-8.e2.
Hansen SE, Whitehill JL, Goto CS, Quintero CA, Darling BE, Davis J. Safety and efficacy of milk and molasses enemas compared with sodium phosphate enemas for the treatment of constipation in a pediatric emergency department. Pediatr Emerg Care. 2011;27(12):1118-20.
Bekkali NL, van den Berg MM, Dijkgraaf MG, et al. Rectal fecal impaction treatment in childhood constipation: Enemas versus high doses oral peg. Pediatrics. 2009;124(6):e1108-15.
Patel H, Law A, Gouin S. Predictive factors for short-term symptom persistence in children after emergency department evaluation for constipation. Arch Pediatr Adolesc Med. 2000;154(12):1204-