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User can click on icon to access the healthcare worker resources page.",{"edges":549},[550,553,556,558,561,564,567,570,573,575,578,581,584,587,589,591,593,595,597,600,603,606,609,611,613,615,618,620,623,626,628,630,632,635,638,640,643,646,648,650,653,656,659,662,665,667,669,671],{"node":551},{"name":552},"Procedural Anxiety and Fear",{"node":554},{"name":555},"Measles",{"node":557},{"name":172},{"node":559},{"name":560},"Agitation",{"node":562},{"name":563},"Anxiety",{"node":565},{"name":566},"Iron Deficiency Anemia",{"node":568},{"name":569},"Influenza",{"node":571},{"name":572},"Advanced Life Support",{"node":574},{"name":53},{"node":576},{"name":577},"Migraine",{"node":579},{"name":580},"Abdominal Pain",{"node":582},{"name":583},"Pneumonia (Community Acquired)",{"node":585},{"name":586},"Chronic Pain",{"node":588},{"name":61},{"node":590},{"name":69},{"node":592},{"name":76},{"node":594},{"name":83},{"node":596},{"name":90},{"node":598},{"name":599},"COVID-19",{"node":601},{"name":602},"Cannabis",{"node":604},{"name":605},"Developmental and Intellectual Disabilities",{"node":607},{"name":608},"Child Abuse",{"node":610},{"name":97},{"node":612},{"name":104},{"node":614},{"name":111},{"node":616},{"name":617},"Critically Ill Neonate",{"node":619},{"name":119},{"node":621},{"name":622},"Eating Disorders",{"node":624},{"name":625},"Febrile Seizures",{"node":627},{"name":126},{"node":629},{"name":133},{"node":631},{"name":141},{"node":633},{"name":634},"Hand Foot and Mouth",{"node":636},{"name":637},"High Flow Nasal Cannula",{"node":639},{"name":148},{"node":641},{"name":642},"Meningitis",{"node":644},{"name":645},"Mental Health Self Assessment Tool",{"node":647},{"name":156},{"node":649},{"name":164},{"node":651},{"name":652},"Procedural Pain",{"node":654},{"name":655},"Procedural Sedation",{"node":657},{"name":658},"Sepsis",{"node":660},{"name":661},"Severe Head Injury",{"node":663},{"name":664},"Sickle Cell Disease",{"node":666},{"name":180},{"node":668},{"name":188},{"node":670},{"name":196},{"node":672},{"name":673},"Visiting the Emergency Department",{"debug":675,"queryAnalyzer":676},[],{"keys":677,"keysLength":678,"keysCount":679,"skippedKeys":680,"skippedKeysSize":681,"skippedKeysCount":681,"skippedTypes":682},"6d6b3d1b2eca580f2aae3985d71dc00ef8fba31240f69e3257cf81d43dbf639a graphql:Query list:menuitem list:audience list:topic cG9zdDoxODY4 cG9zdDo0ODU5 cG9zdDoxNjQ= cG9zdDo5NDc= cG9zdDoxNjA= cG9zdDo0NzAz cG9zdDoxNjE= cG9zdDoxNjM= cG9zdDoyMDE= cG9zdDoyMDI= cG9zdDoyMDM= cG9zdDoyMDU= cG9zdDoyMDY= cG9zdDoyMDg= cG9zdDoyNzkx cG9zdDoyMDk= cG9zdDoyMTA= cG9zdDoyNzky cG9zdDoyMTE= cG9zdDoyNzk2 cG9zdDoyNzkz cG9zdDo0NzA0 cG9zdDoyNzk3 cG9zdDoyNzk0 cG9zdDoyNzk1 cG9zdDoxOTE= cG9zdDoxOTI= cG9zdDoxOTY= cG9zdDoxOTU= cG9zdDoxOTQ= cG9zdDoxOTM= cG9zdDoxMjY= cG9zdDoxMjU= cG9zdDoxOTc= cG9zdDoxOTg= cG9zdDoxOTk= cG9zdDoyMDA= dGVybToxMDg= dGVybToyMA== dGVybTo0ODE= dGVybTo0NzY= dGVybTo0Njk= dGVybTo0NDc= dGVybTo0NTQ= dGVybTo0NTg= dGVybTo0NjE= dGVybTo0NjM= dGVybTo0NjQ= dGVybTo0NzE= dGVybTo0NzI= dGVybTo0MzI= dGVybTo0MzQ= dGVybToyMg== dGVybToyNQ== dGVybToyNw== dGVybToyOA== dGVybTozMA== dGVybTozNQ== dGVybTozMQ== dGVybTozMg== dGVybTo1OQ== dGVybTozMw== dGVybTozNA== dGVybTozNw== dGVybTozNg== dGVybTozOA== dGVybTo0MjE= dGVybToxMTQ= dGVybTo0MA== dGVybTo0MQ== dGVybTo0Mg== dGVybTo2MQ== dGVybToxMTA= dGVybTo0NA== dGVybTo0Ng== dGVybToxMDU= dGVybTo0Nw== dGVybTo0OA== dGVybTo1MQ== dGVybTo1Mg== dGVybTo1NA== dGVybTo1NQ== dGVybTo1Ng== dGVybTo1Nw== dGVybTo1OA== dGVybTo2MA== dGVybToxMDM= cG9zdDoyMzc3 cG9zdDoyMzc1",1274,94,"",0,[],{"data":684,"extensions":1051},{"topics":685},{"edges":686},[687,696,702,709,717,725,733,739,745,751,759,765,773,778,786,794,802,810,818,825,833,841,849,857,865,873,881,889,897,905,913,921,928,936,943,951,959,967,974,981,989,997,1005,1013,1021,1028,1035,1043],{"cursor":688,"node":689},"YXJyYXljb25uZWN0aW9uOjQ4MQ==",{"name":552,"slug":690,"description":691,"translations":692},"procedural-fear-and-anxiety","Anxiety and fears about medical procedures are common in children/youth: two-thirds report needle fear and 10% report needle phobia. Addressing this anxiety/fear is critical, as up to half of children seen in the Emergency Department undergo painful procedures (e.g., IVs, blood tests, catheterizations, wound repair). Procedural pain is complex, involving both physical pain and anxiety/fear. Inadequate management of either increases future anxiety and can lead to healthcare avoidance that persists into adulthood. Managing both improves procedural success and optimizes future care. ",[693],{"languageCode":694,"slug":695},"fr","peur-et-anxiete-procedurale",{"cursor":697,"node":698},"YXJyYXljb25uZWN0aW9uOjQ3Ng==",{"name":555,"slug":699,"description":700,"translations":701},"measles","Measles is a single stranded, enveloped RNA virus belonging to the Morbillivirus genus in the Paramyxoviridae family. The virus can cause a measles infection which starts in the respiratory epithelium of the nasopharynx. Measles is highly contagious.\r\n\r\nMore information coming soon. ",[],{"cursor":703,"node":704},"YXJyYXljb25uZWN0aW9uOjQ2OQ==",{"name":172,"slug":705,"description":171,"translations":706},"respiratory-distress",[707],{"languageCode":694,"slug":708},"detresse-respiratoire-fr",{"cursor":710,"node":711},"YXJyYXljb25uZWN0aW9uOjQ0Nw==",{"name":560,"slug":712,"description":713,"translations":714},"agitation","A clinical tool to guide decision-making when caring for agitated pediatric patients in emergency settings.",[715],{"languageCode":694,"slug":716},"prise-en-charge-du-patient-agite",{"cursor":718,"node":719},"YXJyYXljb25uZWN0aW9uOjQ1NA==",{"name":563,"slug":720,"description":721,"translations":722},"anxiety","Anxiety is a normal emotional and physiological response to uncomfortable, novel or frightening situations. During an emergency department (ED) visit, anxiety can be experienced by any child or adolescent as well as by their caregivers. It may be the primary reason for the visit or develop during assessments, procedures, or investigations. \r\nHow individuals experience anxiety during an ED visit can vary. Approaches to recognize, assess and manage anxiety need to be patient- and family-centred.\r\n",[723],{"languageCode":694,"slug":724},"anxiete",{"cursor":726,"node":727},"YXJyYXljb25uZWN0aW9uOjQ1OA==",{"name":566,"slug":728,"description":729,"translations":730},"iron-deficiency-anemia","Iron deficiency anemia (IDA) is most commonly found in toddlers and adolescents. A primary diagnosis should be identified to explain insufficient intake or excessive loss of iron. The treatment for IDA is supplemental iron. Blood transfusion is restricted to emergency management of patients with hemodynamic instability. ",[731],{"languageCode":694,"slug":732},"iron-deficiency-anemia-fr",{"cursor":734,"node":735},"YXJyYXljb25uZWN0aW9uOjQ2MQ==",{"name":569,"slug":736,"description":737,"translations":738},"influenza","Resources to support informed decision-making in the care of pediatric patients with influenza in emergency settings.",[],{"cursor":740,"node":741},"YXJyYXljb25uZWN0aW9uOjQ2Mw==",{"name":572,"slug":742,"description":743,"translations":744},"advanced-life-support","Pediatric Advanced Life Support (PALS) is a set of clinical guidelines and techniques used to provide emergency care to infants and children experiencing life-threatening medical conditions, such as cardiac arrest, respiratory failure, or shock. It focuses on rapid assessment, early intervention, and the use of advanced airway management, medications, and defibrillation to stabilize and resuscitate pediatric patients. ",[],{"cursor":746,"node":747},"YXJyYXljb25uZWN0aW9uOjQ2NA==",{"name":53,"slug":748,"description":749,"translations":750},"education-session","The tool provides access to all the  TREKK and University of Manitoba's virtual education session videos.",[],{"cursor":752,"node":753},"YXJyYXljb25uZWN0aW9uOjQ3MQ==",{"name":577,"slug":754,"description":755,"translations":756},"migraine","Migraine accounts for up to 30% of pediatric Emergency Department (ED) visits for headache and results in frequent ED revisits. The average age of onset is 7 years in boys and 9 years in girls. Migraine is more common in girls by adolescence. Evidence for ED management of acute migraine attacks in children and adolescents is limited, resulting in significant practice variation.",[757],{"languageCode":694,"slug":758},"migraine-fr",{"cursor":760,"node":761},"YXJyYXljb25uZWN0aW9uOjQ3Mg==",{"name":580,"slug":762,"description":763,"translations":764},"abdominal-pain","Abdominal pain is a common complaint in children, often leading to visits to the emergency department (ED). It can be caused by various conditions, ranging from mild issues like constipation or gas to more serious concerns such as infections or gastrointestinal conditions. Children may experience abdominal pain differently, with younger children having difficulty describing their discomfort. Recognizing, assessing, and managing abdominal pain requires a patient- and family-centred approach to address both the physical and emotional aspects of care.",[],{"cursor":766,"node":767},"YXJyYXljb25uZWN0aW9uOjQzMg==",{"name":583,"slug":768,"description":769,"translations":770},"pneumonia","Viruses are the leading cause of pneumonia in healthy young children, followed by bacteria and rarely, other organisms. These resources focus on uncomplicated community acquired pneumonia (CAP).",[771],{"languageCode":694,"slug":772},"pneumonie",{"cursor":774,"node":775},"YXJyYXljb25uZWN0aW9uOjQzNA==",{"name":586,"slug":776,"description":14,"translations":777},"chronic-pain",[],{"cursor":779,"node":780},"YXJyYXljb25uZWN0aW9uOjIy",{"name":61,"slug":781,"description":782,"translations":783},"aom","Acute Otitis Media (AOM) is common in children under 5 years of age and is often a self-limited illness lasting several days. The mainstay of AOM management is symptom/pain control. In some cases, AOM can be more prolonged or severe and requires antibiotic treatment.",[784],{"languageCode":694,"slug":785},"aom-fr",{"cursor":787,"node":788},"YXJyYXljb25uZWN0aW9uOjI1",{"name":69,"slug":789,"description":790,"translations":791},"anaphylaxis","Anaphylaxis is a serious systemic hypersensitivity reaction that is rapid in onset and can be fatal. The highest incidence of anaphylaxis is in children and youth. The three principal triggers of anaphylaxis are foods, insect stings, and drugs. In Canada, there is an Emergency Department (ED) visit for food allergy approximately every 10 minutes, and up to 80% of anaphylactic reactions in children are triggered by foods such as peanuts, tree nuts, and milk.",[792],{"languageCode":694,"slug":793},"anaphylaxis-fr",{"cursor":795,"node":796},"YXJyYXljb25uZWN0aW9uOjI3",{"name":76,"slug":797,"description":798,"translations":799},"asthma","Approximately one-third of children with asthma presenting to the emergency department (ED) have moderate respiratory distress, and less than 5% will have a severe exacerbation. There are some differences between provincial asthma pathways with regards to PRAM scores and treatment. ",[800],{"languageCode":694,"slug":801},"asthme",{"cursor":803,"node":804},"YXJyYXljb25uZWN0aW9uOjI4",{"name":83,"slug":805,"description":806,"translations":807},"bronchiolitis","Bronchiolitis is a common viral illness. It is most commonly caused by respiratory syncytial virus and typically occurs over the late fall and winter months. Children less than 2 years of age are most commonly affected, with the largest burden of illness being in children less than 12 months of age.",[808],{"languageCode":694,"slug":809},"bronchiolitis-fr",{"cursor":811,"node":812},"YXJyYXljb25uZWN0aW9uOjMw",{"name":90,"slug":813,"description":814,"translations":815},"burns","Burns are a leading cause of unintentional injury and death in children, with the vast majority of cases occurring in the home. Regardless of the burn depth or extent, these injuries can have significant long-term functional, aesthetic, and psychological consequences for the child.",[816],{"languageCode":694,"slug":817},"burns-fr",{"cursor":819,"node":820},"YXJyYXljb25uZWN0aW9uOjM1",{"name":599,"slug":821,"description":14,"translations":822},"covid-19",[823],{"languageCode":694,"slug":824},"covid-19-fr",{"cursor":826,"node":827},"YXJyYXljb25uZWN0aW9uOjMx",{"name":602,"slug":828,"description":829,"translations":830},"cannabis-intoxication","Cannabis contains two well known components, Delta-9 Tetrahydrocannabinol (Δ-9-THC) and Cannabidiol (CBD). The psychoactive properties of cannabis are typically attributed to Δ-9-THC, which is present in variable concentrations dependent on the strain, and absorbed at variable rates dependent on the mode of ingestion. Acute intoxication is rare from cannabidiol (CBD) products unless given in excess or with high THC:CBD ratio. Since Canadian legalization of cannabis for adults, there has been an increasing rate of hospitalization for cannabis exposures in children 14 years and younger.",[831],{"languageCode":694,"slug":832},"cannabis-intoxication-fr",{"cursor":834,"node":835},"YXJyYXljb25uZWN0aW9uOjMy",{"name":605,"slug":836,"description":837,"translations":838},"developmental-and-intellectual-disabilities","Children and youth with developmental or intellectual delays/disorders (DD) use Emergency Department (ED) 1.8 times more frequently than the general pediatric population. This population of patients includes those with autism spectrum disorder (ASD), fetal alcohol spectrum disorder (FASD), or other conditions. This document provides recommendations for the medical approach to these patients to assist in optimizing care.",[839],{"languageCode":694,"slug":840},"caring-for-children-with-developmental-and-intellectual-disabilities-fr",{"cursor":842,"node":843},"YXJyYXljb25uZWN0aW9uOjU5",{"name":608,"slug":844,"description":845,"translations":846},"child-abuse","Children under 3 years of age are at highest risk for serious injuries from abuse. Being alert to findings that suggest abuse will improve early recognition and prevent recurrent, escalating abuse. The extent of the workup performed in the emergency department will vary based on geography, acuity of injury, and services available. Early consultation with a Pediatric Referral Centre or child protection team is recommended.",[847],{"languageCode":694,"slug":848},"child-abuse-fr",{"cursor":850,"node":851},"YXJyYXljb25uZWN0aW9uOjMz",{"name":97,"slug":852,"description":853,"translations":854},"concussion","Concussion is a traumatic brain injury resulting from acceleration/deceleration forces from a direct blow to the head, face, neck or elsewhere on the body with an 'impulsive' force transmitted to the head. Loss of consciousness and amnesia are not required to make the diagnosis.",[855],{"languageCode":694,"slug":856},"concussion-fr",{"cursor":858,"node":859},"YXJyYXljb25uZWN0aW9uOjM0",{"name":104,"slug":860,"description":861,"translations":862},"constipation","Children with functional constipation (FC) often present to the ED with impaction or colicky abdominal pain. The prevalence of FC in infants and toddlers is approximately 20%. While organic causes are responsible for less than 5% of constipation in children, FC may mimic surgical causes of abdominal pain, such as appendicitis, intussusception and bowel obstruction, thus a careful assessment is required before making this diagnosis.",[863],{"languageCode":694,"slug":864},"constipation-fr",{"cursor":866,"node":867},"YXJyYXljb25uZWN0aW9uOjM3",{"name":111,"slug":868,"description":869,"translations":870},"croup","Croup is the most common cause of upper airway obstruction in children. It is characterized by acute onset of barky cough +/- stridor. The typical age of presentation is between 6 months and 5 years with a peak around 2 years. Consider other causes of upper airway obstruction such as bacterial tracheitis, epiglottitis and retropharyngeal abscess in children presenting with severe symptoms and a transient or lack of response to croup treatment.",[871],{"languageCode":694,"slug":872},"croup-fr",{"cursor":874,"node":875},"YXJyYXljb25uZWN0aW9uOjM2",{"name":617,"slug":876,"description":877,"translations":878},"critically-ill-neonate","A clinical tool to guide decision-making when caring for critically ill pediatric patients in emergency settings. \r\nUse in infants 0-28 days. At birth, refer to NRP guidelines. Not intended for preterm infants less than 37 weeks",[879],{"languageCode":694,"slug":880},"critically-ill-neonate-fr",{"cursor":882,"node":883},"YXJyYXljb25uZWN0aW9uOjM4",{"name":119,"slug":884,"description":885,"translations":886},"dka","Diabetic ketoacidosis is a complication of new or existing pediatric diabetes and may be complicated by cerebral injury. Due to this risk, it is treated differently than adult DKA. Health care providers must follow a published pediatric-specific protocol when treating pediatric DKA. Early communication with the diabetes specialist at your pediatric referral site is a key element of the management of these patients. \r\n\r\nKey highlights include dehydration is a key component of DKA pathophysiology; all patients with DKA should receive a 20 ml/kg IV bolus of normal saline or Ringer's lactate over 20 minutes at the initiation of treatment, which can be repeated if the patient remains hypoperfused; ongoing fluids in DKA should be weight-based and account for the significant fluid deficit, with an increased maximum of 500 ml/hr; and every patient in DKA is at risk of cerebral injury before and during treatment, especially if DKA is more severe. Assess every patient with DKA for signs of cerebral injury and follow the TREKK DKA algorithm. \r\n\r\nIn June 2023, TREKK’s DKA resources have been updated to reflect the 2022 International Society for Pediatric and Adolescent Diabetes (ISPAD) guidelines.",[887],{"languageCode":694,"slug":888},"dka-fr",{"cursor":890,"node":891},"YXJyYXljb25uZWN0aW9uOjQyMQ==",{"name":622,"slug":892,"description":893,"translations":894},"eating-disorders","Eating disorders are complex biopsychosocial disorders with significant medical sequelae and a high mortality rate. They exist across diverse populations regardless of age, race, ethnicity, gender, sexual orientation, body habitus, and socioeconomic background. Over the past several years, eating disorder diagnoses have increased globally.",[895],{"languageCode":694,"slug":896},"troubles-alimentaires",{"cursor":898,"node":899},"YXJyYXljb25uZWN0aW9uOjExNA==",{"name":625,"slug":900,"description":901,"translations":902},"febrile-seizures","A febrile seizure is a convulsion accompanied by a fever or illness. The child usually has muscle twitching, jerking or stiffness for a few minutes. The child usually loses consciousness and it is common for the child’s eyes to roll upward. Most children are sleepy afterward and are not responsive to your voice.\r\n\r\nFebrile seizures are common. Between 2-5% of children will have at least one febrile seizure when they are between 6 months and 5 years old. This video will help you to understand what is happening to your child and will help prepare you for your medical visit.",[903],{"languageCode":694,"slug":904},"febrile-seizures-fr",{"cursor":906,"node":907},"YXJyYXljb25uZWN0aW9uOjQw",{"name":126,"slug":908,"description":909,"translations":910},"fever","Neonates (less than or equal to 28 days of age) and young infants (29-60 days of age) with fever account for a significant number of emergency department (ED) visits. At this age, there is an increased risk of urinary tract infections and invasive bacterial infections (IBIs), specifically bacteremia and bacterial meningitis. Most febrile young infants have self-limited viral illnesses, however up to 2-3% harbour life-threatening IBIs. Clinical examination can be unreliable in determining the source or severity of infection. The difficulty lies in differentiating the infant with IBIs from those without, while minimizing the risks of over-investigations. Additionally, infants with IBIs are at risk of poor outcomes if not diagnosed and treated promptly.",[911],{"languageCode":694,"slug":912},"fever-fr",{"cursor":914,"node":915},"YXJyYXljb25uZWN0aW9uOjQx",{"name":133,"slug":916,"description":917,"translations":918},"fractures","Children break bones more easily than adults - so pediatric fractures are very common. There are several unique features of the pediatric musculoskeletal system that need to be considered in management decisions of all of these injuries - growth plates, plasticity, callus formation, remodeling potential, and partial breaks are some of the key ones. Recognition and appropriate management of pediatric fractures by ED providers is critical. While some common minor wrist and ankle fractures can be treated with a less conservative approach encouraging an early return to activities, other fractures if not treated properly can result in long term functional problems for the child and/or be a sign of child maltreatment.",[919],{"languageCode":694,"slug":920},"fractures-fr",{"cursor":922,"node":923},"YXJyYXljb25uZWN0aW9uOjQy",{"name":141,"slug":924,"description":140,"translations":925},"gastroenteritis",[926],{"languageCode":694,"slug":927},"gastroenteritis-fr",{"cursor":929,"node":930},"YXJyYXljb25uZWN0aW9uOjYx",{"name":634,"slug":931,"description":932,"translations":933},"hand-foot-mouth","Hand-foot-mouth disease or coxsackie is a common viral illness that most children get at some point that can cause symptoms including fever, rash, spots in the mouth and decreased feeding. This short video will help you to understand what to expect when your child has coxsackie and how you can care for them.",[934],{"languageCode":694,"slug":935},"hand-foot-mouth-fr",{"cursor":937,"node":938},"YXJyYXljb25uZWN0aW9uOjExMA==",{"name":637,"slug":939,"description":14,"translations":940},"high-flow-nasal-cannula",[941],{"languageCode":694,"slug":942},"high-flow-nasal-cannula-fr",{"cursor":944,"node":945},"YXJyYXljb25uZWN0aW9uOjQ0",{"name":148,"slug":946,"description":947,"translations":948},"intussusception","Intussusception is invagination of the intestine into an adjacent segment, most commonly involving the ileocecal valve. This process occludes blood supply to the bowel and can progress from tissue ischemia to necrosis/perforation. It is most likely to be idiopathic, but can be caused by a variety of pathological lead points.",[949],{"languageCode":694,"slug":950},"intussusception-fr",{"cursor":952,"node":953},"YXJyYXljb25uZWN0aW9uOjQ2",{"name":642,"slug":954,"description":955,"translations":956},"meningitis","Most cases of childhood meningitis are caused by an enterovirus. Bacterial meningitis is less common, with 90% of cases occurring in children less than 5 years of age. Bacterial meningitis has a mortality rate of 20% in infants and 2% in children; neurologic sequalae occur in approximately one-third of children who survive their infection. Early diagnosis and treatment of bacterial meningitis is associated with better outcomes. Viral meningitis is a diagnosis of exclusion.",[957],{"languageCode":694,"slug":958},"meningitis-fr",{"cursor":960,"node":961},"YXJyYXljb25uZWN0aW9uOjEwNQ==",{"name":645,"slug":962,"description":963,"translations":964},"mental-health-self-assessment-tool","On this page, you will find evidence-based tools and information surrounding pediatric mental health concerns. The information provided on TREKK.ca is designed to complement, not replace, the relationship between a patient and their own physician or healthcare provider.",[965],{"languageCode":694,"slug":966},"mental-health-self-assessment-tool-fr",{"cursor":968,"node":969},"YXJyYXljb25uZWN0aW9uOjQ3",{"name":156,"slug":970,"description":155,"translations":971},"multisystem-trauma",[972],{"languageCode":694,"slug":973},"multisystem-trauma-fr",{"cursor":975,"node":976},"YXJyYXljb25uZWN0aW9uOjQ4",{"name":164,"slug":977,"description":163,"translations":978},"pain-treatment",[979],{"languageCode":694,"slug":980},"pain-treatment-fr",{"cursor":982,"node":983},"YXJyYXljb25uZWN0aW9uOjUx",{"name":652,"slug":984,"description":985,"translations":986},"procedural-pain","Common medical procedures used to assess and treat children can cause significant pain and distress. Untreated pain has short-term (pain and distress for the child, caregivers, and healthcare providers; prolonged procedure time; slower healing) and long-term consequences (increased sensitivity to pain; avoidance of healthcare settings; needle phobia, higher levels of anxiety before a procedure). Timely and effective multi-modal pain care improves procedure success rates, prevents the need for repeated attempts, improves patient flow, and improves patient and caregiver satisfaction. Before initiating any procedure: consider whether it is truly necessary, batch procedures together, optimize pain management, and engage caregivers in planning/decision-making. ",[987],{"languageCode":694,"slug":988},"procedural-pain-fr",{"cursor":990,"node":991},"YXJyYXljb25uZWN0aW9uOjUy",{"name":655,"slug":992,"description":993,"translations":994},"procedural-sedation","A brief summary of current knowledge needed to perform safe and effective procedural sedation in children.",[995],{"languageCode":694,"slug":996},"procedural-sedation-fr",{"cursor":998,"node":999},"YXJyYXljb25uZWN0aW9uOjU0",{"name":658,"slug":1000,"description":1001,"translations":1002},"sepsis","Sepsis is a systemic response to infection; it is a leading cause of morbidity and mortality worldwide. Early recognition, aggressive resuscitation (fluids, metabolic correction, antibiotics) and escalation of care (vasoactive medications) are key to improving patient outcomes.",[1003],{"languageCode":694,"slug":1004},"sepsis-fr",{"cursor":1006,"node":1007},"YXJyYXljb25uZWN0aW9uOjU1",{"name":661,"slug":1008,"description":1009,"translations":1010},"severe-head-injury","Head trauma is considered severe in a child with a Glasgow Coma Scale (GCS) score of ≤ 8. These children often have intracranial injury identified on neuroimaging and all have suffered traumatic brain injury (TBI). Injury is the leading cause of death in children >1 year of age, and TBI is the most significant cause of death and disability across all ages.",[1011],{"languageCode":694,"slug":1012},"severe-head-injury-fr",{"cursor":1014,"node":1015},"YXJyYXljb25uZWN0aW9uOjU2",{"name":664,"slug":1016,"description":1017,"translations":1018},"scd","Sickle cell disease (SCD) is a genetic disorder of hemoglobin, in which sickling of red blood cells results in hemolysis and vasoocclusion. Newborn screening has led to early identification of SCD in many regions across Canada. While homozygous SCD (HbSS) is the most severe, other sickling syndromes (e.g., HbSC) may present similarly.",[1019],{"languageCode":694,"slug":1020},"scd-fr",{"cursor":1022,"node":1023},"YXJyYXljb25uZWN0aW9uOjU3",{"name":180,"slug":1024,"description":179,"translations":1025},"status-epilepticus",[1026],{"languageCode":694,"slug":1027},"status-epilepticus-fr",{"cursor":1029,"node":1030},"YXJyYXljb25uZWN0aW9uOjU4",{"name":188,"slug":1031,"description":187,"translations":1032},"suicidal-risk-screening-assessment",[1033],{"languageCode":694,"slug":1034},"suicidal-risk-screening-assessment-fr",{"cursor":1036,"node":1037},"YXJyYXljb25uZWN0aW9uOjYw",{"name":196,"slug":1038,"description":1039,"translations":1040},"uti","UTI is among the most common serious bacterial infections seen in infants and children. UTI with fever is indicative of an upper tract infection/pyelonephritis, as opposed to afebrile cystitis. It is important to diagnose and empirically treat febrile UTIs in infants and children, as delayed treatment may increase the risk of bacteremia. There are a number of risk factors associated with increased rates of UTI in young children such as age, gender and height of fever. ",[1041],{"languageCode":694,"slug":1042},"uti-fr",{"cursor":1044,"node":1045},"YXJyYXljb25uZWN0aW9uOjEwMw==",{"name":673,"slug":1046,"description":1047,"translations":1048},"visiting-ed","The Emergency Department (ED) is a place where people go for immediate care.\r\nVisiting the ED can be scary and overwhelming, especially when you don’t know what to expect. We hope these resources helps reduce stress and helps you prepare.\r\n",[1049],{"languageCode":694,"slug":1050},"visiting-ed-fr",{"debug":1052,"queryAnalyzer":1053},[],{"keys":1054,"keysLength":1055,"keysCount":1056,"skippedKeys":680,"skippedKeysSize":681,"skippedKeysCount":681,"skippedTypes":1057},"9ba504182e5375d8ee802ccd07f58575ad4f11b79a3c746ac62c55429115da0f graphql:Query list:topic dGVybTo0ODE= dGVybTo0NzY= dGVybTo0Njk= dGVybTo0NDc= dGVybTo0NTQ= dGVybTo0NTg= dGVybTo0NjE= dGVybTo0NjM= dGVybTo0NjQ= dGVybTo0NzE= dGVybTo0NzI= dGVybTo0MzI= dGVybTo0MzQ= dGVybToyMg== dGVybToyNQ== dGVybToyNw== dGVybToyOA== dGVybTozMA== dGVybTozNQ== dGVybTozMQ== dGVybTozMg== dGVybTo1OQ== dGVybTozMw== dGVybTozNA== dGVybTozNw== dGVybTozNg== dGVybTozOA== dGVybTo0MjE= dGVybToxMTQ= dGVybTo0MA== dGVybTo0MQ== dGVybTo0Mg== dGVybTo2MQ== dGVybToxMTA= dGVybTo0NA== dGVybTo0Ng== dGVybToxMDU= dGVybTo0Nw== dGVybTo0OA== dGVybTo1MQ== dGVybTo1Mg== dGVybTo1NA== dGVybTo1NQ== dGVybTo1Ng== dGVybTo1Nw== dGVybTo1OA== dGVybTo2MA== dGVybToxMDM=",713,51,[],{"data":1059,"extensions":1153},{"footer_1":1060,"footer_2":1078,"footer_3":1105,"footer_privacy":1118,"social":1125,"footer":1139},{"edges":1061},[1062,1067,1072],{"cursor":1063,"node":1064},"YXJyYXljb25uZWN0aW9uOjE2Ng==",{"label":29,"uri":31,"target":14,"menu":1065},{"node":1066},{"name":12},{"cursor":1068,"node":1069},"YXJyYXljb25uZWN0aW9uOjIwMzg=",{"label":36,"uri":38,"target":14,"menu":1070},{"node":1071},{"name":12},{"cursor":1073,"node":1074},"YXJyYXljb25uZWN0aW9uOjE2OA==",{"label":1075,"uri":13,"target":14,"menu":1076},"All Topics",{"node":1077},{"name":12},{"edges":1079},[1080,1085,1090,1095,1100],{"cursor":1081,"node":1082},"YXJyYXljb25uZWN0aW9uOjE2OQ==",{"label":441,"uri":435,"target":14,"menu":1083},{"node":1084},{"name":448},{"cursor":1086,"node":1087},"YXJyYXljb25uZWN0aW9uOjE3MA==",{"label":448,"uri":481,"target":14,"menu":1088},{"node":1089},{"name":448},{"cursor":1091,"node":1092},"YXJyYXljb25uZWN0aW9uOjE3MQ==",{"label":455,"uri":487,"target":14,"menu":1093},{"node":1094},{"name":448},{"cursor":1096,"node":1097},"YXJyYXljb25uZWN0aW9uOjE3Mg==",{"label":462,"uri":493,"target":14,"menu":1098},{"node":1099},{"name":448},{"cursor":1101,"node":1102},"YXJyYXljb25uZWN0aW9uOjIxMjk=",{"label":469,"uri":499,"target":14,"menu":1103},{"node":1104},{"name":448},{"edges":1106},[1107,1113],{"cursor":1108,"node":1109},"YXJyYXljb25uZWN0aW9uOjE3NA==",{"label":506,"uri":507,"target":14,"menu":1110},{"node":1111},{"name":1112},"Info",{"cursor":1114,"node":1115},"YXJyYXljb25uZWN0aW9uOjE3Mw==",{"label":510,"uri":511,"target":14,"menu":1116},{"node":1117},{"name":1112},{"edges":1119},[1120],{"cursor":1121,"node":1122},"YXJyYXljb25uZWN0aW9uOjE3NQ==",{"label":1123,"uri":1124,"target":14},"Terms of Use","/terms-of-use/",{"edges":1126},[1127,1130,1133,1136],{"cursor":1128,"node":1129},"YXJyYXljb25uZWN0aW9uOjE5Nw==",{"label":516,"url":517,"target":14},{"cursor":1131,"node":1132},"YXJyYXljb25uZWN0aW9uOjE5OA==",{"label":520,"url":521,"target":14},{"cursor":1134,"node":1135},"YXJyYXljb25uZWN0aW9uOjE5OQ==",{"label":524,"url":525,"target":14},{"cursor":1137,"node":1138},"YXJyYXljb25uZWN0aW9uOjIwMA==",{"label":528,"url":529,"target":14},{"optionsTheme":1140},{"newsletterTitle":1141,"newsletterTitleFr":1142,"newsletterDescription":1143,"newsletterDescriptionFr":1144,"newsletterUrl":1145,"newsletterUrlFr":1149,"landAcknowledgement":1151,"landAcknowledgementFr":1152},"Subscribe to our Newsletter","Abonnez-vous à notre bulletin d'information","When you subscribe to this e-update, new issues will be sent to your email address the moment they are published.","Lorsque vous vous abonnez à cette mise à jour électronique, les nouveaux numéros seront envoyés à votre adresse e-mail dès leur publication.",{"title":1146,"url":1147,"target":1148},"Subscribe","https://trekk.us16.list-manage.com/subscribe?u=31840b6f27d1074425db8898a&id=2c90e9e1a9","_blank",{"title":1150,"url":1147,"target":1148},"S'inscrire","\u003Cp>TREKK acknowledges that our network is situated on the unceded and ancestral territories of diverse Indigenous Peoples across Turtle Island. \u003C/p>\n\u003Cp>From coast to coast to coast, we respect and acknowledge Inuit, Métis, and First Nations Peoples as the traditional stewards of the lands we work and live on. For those of us who are settlers, we recognize that processes of colonization continue to impact Indigenous Peoples today. TREKK is committed to working toward cultural safety, decolonization, and reconciliation.\u003C/p>\n","\u003Cp>TREKK reconnaît que notre réseau est situé sur les territoires non cédés et ancestraux de divers peuples autochtones de l'Île de la Tortue.\u003C/p>\n\u003Cp>D’un océan à l’autre, nous respectons et reconnaissons les Inuits, les Métis et les Premières Nations en tant que gardiens traditionnels des terres sur lesquelles nous travaillons et vivons. Pour ceux d’entre nous qui sont des colons, nous reconnaissons que les processus de colonisation continuent d’avoir un impact sur les peuples autochtones aujourd’hui. TREKK s’engage à œuvrer en faveur de la sécurité culturelle, de la décolonisation et de la réconciliation.\u003C/p>\n",{"debug":1154,"queryAnalyzer":1155},[],{"keys":1156,"keysLength":1157,"keysCount":1158,"skippedKeys":680,"skippedKeysSize":681,"skippedKeysCount":681,"skippedTypes":1159},"d9a1e4a4227d63ecc282d2b69b4b64d07ba73e19765e9d47f113fdada604cd45 graphql:Query list:menuitem cG9zdDoxNjY= cG9zdDoyMDM4 cG9zdDoxNjg= cG9zdDoxNjk= cG9zdDoxNzA= cG9zdDoxNzE= cG9zdDoxNzI= cG9zdDoyMTI5 cG9zdDoxNzQ= cG9zdDoxNzM= cG9zdDoxNzU= cG9zdDoxOTc= cG9zdDoxOTg= cG9zdDoxOTk= cG9zdDoyMDA= YWNmX29wdGlvbnNfcGFnZTp0aGVtZS1zZXR0aW5ncw== dGVybTo3Ng== dGVybTo3Nw== dGVybTo3OA==",371,22,[],{"data":1161,"extensions":1236},{"resource":1162},{"title":1163,"databaseId":1164,"excerpt":680,"uri":1165,"language":1166,"translations":1168,"ptResources":1193},"Evidence Repository: Iron Deficiency Anemia",3953,"/resources/evidence-repository-iron-deficiency-anemia/",{"code":1167},"en",[1169],{"slug":1170,"uri":1171,"title":1172,"languageCode":694,"ptResources":1173},"referentiel-medical-anemie-ferriprive","/fr/resources/referentiel-medical-anemie-ferriprive/","Référentiel médical : Anémie ferriprive pédiatrique",{"mainTitle":1174,"subTitle":14,"media":1175,"pdf":1176,"link":1183,"videos":14,"sections":1185},"Anémie ferriprive","PDF",{"cursor":1177,"node":1178},"YXJyYXljb25uZWN0aW9uOjM5NTc=",{"fileSize":1179,"mediaItemUrl":1180,"translations":1181},427498,"https://cms.trekk.ca/wp-content/uploads/2024/09/2024_08_09-Iron-Deficiency-Anemia-Evidence-Repository-v1.0-FR.pdf",[1182],{"languageCode":694,"mediaItemUrl":1180},{"title":680,"target":680,"url":1184},"https://cms.trekk.ca/wp-content/uploads/2024/09/2024_08_29-Iron-Deficiency-Anemia-Evidence-Repository-v1.0.pdf",[1186,1188,1189,1190,1191,1192],{"__typename":1187},"PtResourcesSectionsContentLayout",{"__typename":1187},{"__typename":1187},{"__typename":1187},{"__typename":1187},{"__typename":1187},{"publish":1194,"description":14,"eyebrow":1195,"mainTitle":566,"subTitle":14,"lastUpdated":1196,"developed":14,"developedBy":14,"developedByCopy":14,"underReview":1194,"englishOnlyFlag":1194,"multipleLanguages":1194,"mainImage":14,"media":1175,"pdf":1197,"link":1201,"videos":14,"footnote":14,"sections":1202,"audience":1220,"topic":1225,"type":1230},false,"Evidence Repository","2023-09-01T00:00:00+00:00",{"cursor":1198,"node":1199},"YXJyYXljb25uZWN0aW9uOjM5MjU=",{"fileSize":1200,"mediaItemUrl":1184},560672,{"title":680,"target":680,"url":1184},[1203,1206,1208,1211,1214,1217],{"__typename":1187,"title":1204,"subTitle":1194,"content":1205},"EVIDENCE REPOSITORIES","\u003Cp>This evidence repository is a collection of best available resources and evidence collated by a knowledge synthesis team at Alberta Research for Health Evidence (\u003Ca href=\"https://www.ualberta.ca/pediatrics/pediatric-research/affiliated-research-units/alberta-research-centre-for-health-evidence-arche/index.html\">ARCHE\u003C/a>) and the clinical content team.\u003C/p>\n\u003Cp>The knowledge synthesis team utilizes a pyramid-shaped framework, built upon the \u003Ca href=\"https://ebn.bmj.com/content/8/1/4\" target=\"_blank\" rel=\"noopener\">“4S” hierarchy of\u003C/a> \u003Ca href=\"https://ebn.bmj.com/content/8/1/4\" target=\"_blank\" rel=\"noopener\">evidence model\u003C/a>, to provide detailed evidence appropriate to meet stakeholders’ needs. They search a combination of databases (Cochrane Library, PubMed, TRIP Database) and web-based search engines (Google, Google Scholar) to locate evidence for the knowledge pyramids. Publication types sought in the initial topic searches are organized into five levels that determine the order in which resources are presented:\u003C/p>\n\u003Col>\n\u003Cli>Bottom Line Recommendations\u003C/li>\n\u003Cli>Clinical Practice Guidelines and Pathways\u003C/li>\n\u003Cli>Overviews and Summaries of Systematic Reviews\u003C/li>\n\u003Cli>Systematic Reviews\u003C/li>\n\u003Cli>Key Studies\u003C/li>\n\u003C/ol>\n\u003Cp>Where applicable resources for families and parents are also listed.\u003C/p>\n",{"__typename":1187,"title":14,"subTitle":1194,"content":1207},"\u003Cp>The knowledge synthesis team collaborates with the clinical content team to select the most relevant guidelines, reviews, and key studies, which can be found below. This evidence repository is not intended to be an exhaustive list of resources for a topic, but rather a curated list of current, evidence-based resources, based on expert consensus of relevance and usability for a general emergency department setting. Every effort is made to identify resources that are open access (i.e. publicly available, free of charge, not requiring a subscription).\u003C/p>\n\u003Cp>More information about the creation of our evidence repositories can be found \u003Ca href=\"https://pubmed.ncbi.nlm.nih.gov/28537762/\">here\u003C/a>.\u003C/p>\n",{"__typename":1187,"title":1209,"subTitle":1194,"content":1210},"Content Team","\u003Cp>Thank you to the following clinical content experts and Knowledge Synthesis team who led the development of this evidence repository.\u003C/p>\n\u003Cp>\u003Cstrong>Mathew Speckert\u003C/strong>, MEd, MD, FRCPC \u003Cem>Children’s Hospital of Eastern Ontario (\u003Ca href=\"https://www.cheo.on.ca/en/index.aspx\">CHEO\u003C/a>)\u003C/em>\u003C/p>\n\u003Cp>\u003Cstrong>Habeeb Alsaeed\u003C/strong>, MD, FRCPC, \u003Cem>Children’s Hospital of Eastern Ontario (\u003Ca href=\"https://www.cheo.on.ca/en/index.aspx\">CHEO\u003C/a>)\u003C/em>\u003C/p>\n\u003Cp>\u003Cstrong>Graham Chamberlain\u003C/strong>, MD, FRCPC\u003Cem>, \u003Ca href=\"https://www.qhc.on.ca/\">Belleville General Hospital\u003C/a>\u003C/em>\u003C/p>\n\u003Cp>\u003Cstrong>Elaine Leung\u003C/strong>, MD, FRCPC, \u003Cem>Children’s Hospital of Eastern Ontario (\u003Ca href=\"https://www.cheo.on.ca/en/index.aspx\">CHEO\u003C/a>)\u003C/em>\u003C/p>\n\u003Cp>\u003Cstrong>Liza Bialy,\u003C/strong> BSc, MPH, \u003Cem>Knowledge Synthesis Project Coordinator, Alberta Research Centre for Health Evidence, Department of  Pediatrics, University of Alberta\u003C/em>\u003C/p>\n\u003Cp>\u003Cstrong>Sarah Elliott\u003C/strong>, PhD, \u003Cem>Assistant Director, Alberta Research Centre for Health Evidence, Department of Pediatrics, University of  Alberta\u003C/em>\u003C/p>\n",{"__typename":1187,"title":1212,"subTitle":1194,"content":1213},"Clinical Practice Guidelines And Pathways","\u003Col>\n\u003Cli>O’Brien SH, Badawy SM, Rotz SJ, et al. \u003Ca href=\"https://choosingwiselycanada.org/recommendation/transfusion-medicine/\" target=\"_blank\" rel=\"noopener\">The ASH-ASPHO choosing wisely campaign: 5 hematologic tests\u003C/a> \u003Ca href=\"https://choosingwiselycanada.org/recommendation/transfusion-medicine/\" target=\"_blank\" rel=\"noopener\">and treatments to question\u003C/a>. Blood Adv. 2022;6(2):679-85.\u003C/li>\n\u003Cli>Numan S, Kaluza K. \u003Ca href=\"https://pubmed.ncbi.nlm.nih.gov/32936683/\" target=\"_blank\" rel=\"noopener\">Systematic review of guidelines for the diagnosis and treatment of iron deficiency\u003C/a> \u003Ca href=\"https://pubmed.ncbi.nlm.nih.gov/32936683/\" target=\"_blank\" rel=\"noopener\">anemia using intravenous iron across multiple indications\u003C/a>. Curr Med Res Opin. 2020;36(11):1769-82.\u003C/li>\n\u003Cli>Mattiello V, Schmugge M, Hengartner H, et al. \u003Ca href=\"https://pubmed.ncbi.nlm.nih.gov/32020331/\" target=\"_blank\" rel=\"noopener\">Diagnosis and management of iron deficiency in \u003C/a>\u003Ca href=\"https://pubmed.ncbi.nlm.nih.gov/34557594/\" target=\"_blank\" rel=\"noopener\">children\u003C/a> \u003Ca href=\"https://pubmed.ncbi.nlm.nih.gov/32020331/\" target=\"_blank\" rel=\"noopener\">with or without anemia: Consensus recommendations of the SPOG pediatric hematology working group\u003C/a>. Eur J Pediatr. 2020;179(4):527-45.\u003C/li>\n\u003Cli>Province of British Columbia. \u003Ca href=\"https://pubmed.ncbi.nlm.nih.gov/24972460/\" target=\"_blank\" rel=\"noopener\">Iron deficiency\u003C/a> \u003Ca href=\"https://www2.gov.bc.ca/gov/content/health/practitioner-professional-resources/bc-guidelines/iron-deficiency\" target=\"_blank\" rel=\"noopener\">– Diagnosis and management. 2019\u003C/a>.\u003C/li>\n\u003Cli>Doctor A, Cholette JM, Remy KE, et al. \u003Ca href=\"https://pubmed.ncbi.nlm.nih.gov/30161064/\" target=\"_blank\" rel=\"noopener\">Recommendations on RBC transfusion in general critically ill\u003C/a> \u003Ca href=\"https://pubmed.ncbi.nlm.nih.gov/30161064/\" target=\"_blank\" rel=\"noopener\">children based on hemoglobin and/or physiologic thresholds from the pediatric critical care transfusion and\u003C/a> \u003Ca href=\"https://pubmed.ncbi.nlm.nih.gov/30161064/\" target=\"_blank\" rel=\"noopener\">anemia expertise initiative\u003C/a>. Pediatr Crit Care Med. 2018;19(9S Suppl 1):S98-s113.\u003C/li>\n\u003Cli>Kemper AR, Fan T, Grossman DC, Phipps MG. \u003Ca href=\"https://pubmed.ncbi.nlm.nih.gov/29070541/\" target=\"_blank\" rel=\"noopener\">Gaps in evidence regarding \u003C/a>\u003Ca href=\"https://pubmed.ncbi.nlm.nih.gov/32014276/\" target=\"_blank\" rel=\"noopener\">iron \u003C/a>\u003Ca href=\"https://pubmed.ncbi.nlm.nih.gov/28562517/\" target=\"_blank\" rel=\"noopener\">deficiency anemia\u003C/a>\u003Ca href=\"https://pubmed.ncbi.nlm.nih.gov/29070541/\" target=\"_blank\" rel=\"noopener\"> in\u003C/a> \u003Ca href=\"https://pubmed.ncbi.nlm.nih.gov/29070541/\" target=\"_blank\" rel=\"noopener\">pregnant women and young children: Summary of us preventive services task force recommendations\u003C/a>. Am J Clin Nutr. 2017;106(Suppl 6):1555s-8s.\u003C/li>\n\u003Cli>World Health Organization. \u003Ca href=\"https://cdn.who.int/media/docs/default-source/micronutrients/ferritin-guideline/ferritin-guidelines-executivesummary.pdf?sfvrsn=8c98babb_2.\" target=\"_blank\" rel=\"noopener\">Who guideline on use of ferritin concentrations to assess iron status in\u003C/a> \u003Ca href=\"https://cdn.who.int/media/docs/default-source/micronutrients/ferritin-guideline/ferritin-guidelines-executivesummary.pdf?sfvrsn=8c98babb_2.\" target=\"_blank\" rel=\"noopener\">individuals and populations\u003C/a>. 2016.\u003C/li>\n\u003Cli>Siu AL. \u003Ca href=\"https://pubmed.ncbi.nlm.nih.gov/26347426/\" target=\"_blank\" rel=\"noopener\">Screening for iron deficiency anemia in young children: USPSTF recommendation statement\u003C/a>. Pediatrics. 2015;136(4):746-52.\u003C/li>\n\u003C/ol>\n",{"__typename":1187,"title":1215,"subTitle":1194,"content":1216},"Systematic Reviews","\u003Col>\n\u003Cli>Moscheo C, Licciardello M, Samperi P, et al. \u003Ca href=\"https://pubmed.ncbi.nlm.nih.gov/35448476/\" target=\"_blank\" rel=\"noopener\">New insights into \u003C/a>\u003Ca href=\"https://pubmed.ncbi.nlm.nih.gov/32014276/\" target=\"_blank\" rel=\"noopener\">iron \u003C/a>\u003Ca href=\"https://pubmed.ncbi.nlm.nih.gov/28562517/\" target=\"_blank\" rel=\"noopener\">deficiency anemia\u003C/a>\u003Ca href=\"https://pubmed.ncbi.nlm.nih.gov/20404750/\" target=\"_blank\" rel=\"noopener\"> in \u003C/a>\u003Ca href=\"https://pubmed.ncbi.nlm.nih.gov/34557594/\" target=\"_blank\" rel=\"noopener\">children\u003C/a>\u003Ca href=\"https://pubmed.ncbi.nlm.nih.gov/35448476/\" target=\"_blank\" rel=\"noopener\">: A\u003C/a> \u003Ca href=\"https://pubmed.ncbi.nlm.nih.gov/35448476/\" target=\"_blank\" rel=\"noopener\">practical review\u003C/a>. Metabolites. 2022;12(4).\u003C/li>\n\u003Cli>Gedfie S, Getawa S, Melku M. \u003Ca href=\"https://pubmed.ncbi.nlm.nih.gov/35832654/\" target=\"_blank\" rel=\"noopener\">Prevalence and associated factors of iron deficiency and iron\u003C/a> \u003Ca href=\"https://pubmed.ncbi.nlm.nih.gov/35832654/\" target=\"_blank\" rel=\"noopener\">deficiency anemia among under-5 children: A systematic review \u003C/a>\u003Ca href=\"https://pubmed.ncbi.nlm.nih.gov/25572192/\" target=\"_blank\" rel=\"noopener\">and meta-analysis\u003C/a>. Glob Pediatr Health. 2022;9:2333794×221110860.\u003C/li>\n\u003Cli>Aksan A, Zepp F, Anand S, Stein J. \u003Ca href=\"https://pubmed.ncbi.nlm.nih.gov/36056175/\" target=\"_blank\" rel=\"noopener\">Intravenous ferric carboxymaltose for the management of iron\u003C/a> \u003Ca href=\"https://pubmed.ncbi.nlm.nih.gov/36056175/\" target=\"_blank\" rel=\"noopener\">deficiency and iron deficiency anaemia in children and adolescents: A review\u003C/a>. Eur J Pediatr. 2022;181(11):3781-93.\u003C/li>\n\u003Cli>Shah AA, Donovan K, Seeley C, et al. \u003Ca href=\"https://pubmed.ncbi.nlm.nih.gov/34767026/\" target=\"_blank\" rel=\"noopener\">Risk of infection associated with administration of\u003C/a> \u003Ca href=\"https://pubmed.ncbi.nlm.nih.gov/34767026/\" target=\"_blank\" rel=\"noopener\">intravenous iron: A systematic review and meta-analysis\u003C/a>. JAMA Netw Open. 2021;4(11):e2133935.\u003C/li>\n\u003Cli>Mohd Rosli RR, Norhayati MN, Ismail SB. \u003Ca href=\"https://pubmed.ncbi.nlm.nih.gov/33520436/\" target=\"_blank\" rel=\"noopener\">Effectiveness of iron polymaltose complex in treatment\u003C/a> \u003Ca href=\"https://pubmed.ncbi.nlm.nih.gov/33520436/\" target=\"_blank\" rel=\"noopener\">and prevention of iron deficiency anemia in children: A systematic review and meta-analysis\u003C/a>. PeerJ. 2021;9:e10527.\u003C/li>\n\u003Cli>Gordon M, Sinopoulou V, Iheozor-Ejiofor Z, et al. \u003Ca href=\"https://pubmed.ncbi.nlm.nih.gov/33471939/\" target=\"_blank\" rel=\"noopener\">Interventions for treating iron deficiency anaemia\u003C/a> \u003Ca href=\"https://pubmed.ncbi.nlm.nih.gov/33471939/\" target=\"_blank\" rel=\"noopener\">in inflammatory bowel disease\u003C/a>. Cochrane Database Syst Rev. 2021;1(1):Cd013529.\u003C/li>\n\u003Cli>Lim W, Afif W, Knowles S, et al. \u003Ca href=\"https://pubmed.ncbi.nlm.nih.gov/30937914/\" target=\"_blank\" rel=\"noopener\">Canadian expert consensus: Management of hypersensitivity\u003C/a> \u003Ca href=\"https://pubmed.ncbi.nlm.nih.gov/30937914/\" target=\"_blank\" rel=\"noopener\">reactions to intravenous iron in adults\u003C/a>. Vox Sang. 2019;114(4):363-73.\u003C/li>\n\u003Cli>Mantadakis E. \u003Ca href=\"https://pubmed.ncbi.nlm.nih.gov/26376214/\" target=\"_blank\" rel=\"noopener\">Advances in pediatric intravenous iron therapy\u003C/a>. Pediatr Blood Cancer. 2016;63(1):11-6.\u003C/li>\n\u003Cli>Auerbach M, Deloughery T. \u003Ca href=\"https://pubmed.ncbi.nlm.nih.gov/27913463/\" target=\"_blank\" rel=\"noopener\">Single-dose intravenous iron for iron deficiency: A new paradigm\u003C/a>. Hematology Am Soc Hematol Educ Program. 2016;2016(1):57-66.\u003C/li>\n\u003Cli>Auerbach M, Adamson JW. \u003Ca href=\"https://pubmed.ncbi.nlm.nih.gov/26408108/\" target=\"_blank\" rel=\"noopener\">How we diagnose and treat iron deficiency anemia\u003C/a>. Am J Hematol. 2016;91(1):31-8.\u003C/li>\n\u003Cli>Peyrin-Biroulet L, Williet N, Cacoub P. \u003Ca href=\"https://pubmed.ncbi.nlm.nih.gov/26561626/\" target=\"_blank\" rel=\"noopener\">Guidelines on the diagnosis and treatment of iron deficiency\u003C/a> \u003Ca href=\"https://pubmed.ncbi.nlm.nih.gov/26561626/\" target=\"_blank\" rel=\"noopener\">across indications: A systematic review\u003C/a>. Am J Clin Nutr. 2015;102(6):1585-94.\u003C/li>\n\u003Cli>McDonagh MS, Blazina I, Dana T, et al. \u003Ca href=\"https://pubmed.ncbi.nlm.nih.gov/25825534/\" target=\"_blank\" rel=\"noopener\">Screening and routine supplementation for iron deficiency\u003C/a> \u003Ca href=\"https://pubmed.ncbi.nlm.nih.gov/25825534/\" target=\"_blank\" rel=\"noopener\">anemia: A systematic review\u003C/a>. Pediatrics. 2015;135(4):723-33.\u003C/li>\n\u003Cli>Avni T, Bieber A, Grossman A, et al. \u003Ca href=\"https://pubmed.ncbi.nlm.nih.gov/25572192/\">The safety of intravenous iron preparations: Systematic review and meta-analysis.\u003C/a> Mayo Clin Proc. 2015;90(1):12-23.\u003C/li>\n\u003Cli>Powers JM, Buchanan GR. \u003Ca href=\"https://pubmed.ncbi.nlm.nih.gov/25064710/\" target=\"_blank\" rel=\"noopener\">Diagnosis and management of iron deficiency anemia\u003C/a>. Hematol Oncol Clin North Am. 2014;28(4):729-45, vi-vii.\u003C/li>\n\u003Cli>De Andrade Cairo RC, Rodrigues Silva L, Carneiro Bustani N, Ferreira Marques CD. \u003Ca href=\"https://pubmed.ncbi.nlm.nih.gov/24972460/\" target=\"_blank\" rel=\"noopener\">Iron deficiency\u003C/a> \u003Ca href=\"https://pubmed.ncbi.nlm.nih.gov/24972460/\" target=\"_blank\" rel=\"noopener\">anemia in adolescents: A literature review\u003C/a>. Nutr Hosp. 2014;29(6):1240-9.\u003C/li>\n\u003C/ol>\n",{"__typename":1187,"title":1218,"subTitle":1194,"content":1219},"Key Studies","\u003Col>\n\u003Cli>Speckert M, Ramic L, Mitsakakis N, et al. \u003Ca href=\"https://pubmed.ncbi.nlm.nih.gov/36865758/\" target=\"_blank\" rel=\"noopener\">Severe \u003C/a>\u003Ca href=\"https://pubmed.ncbi.nlm.nih.gov/32014276/\" target=\"_blank\" rel=\"noopener\">iron \u003C/a>\u003Ca href=\"https://pubmed.ncbi.nlm.nih.gov/28562517/\" target=\"_blank\" rel=\"noopener\">deficiency anemia\u003C/a>\u003Ca href=\"https://pubmed.ncbi.nlm.nih.gov/36865758/\" target=\"_blank\" rel=\"noopener\"> in the paediatric\u003C/a> \u003Ca href=\"https://pubmed.ncbi.nlm.nih.gov/36865758/\" target=\"_blank\" rel=\"noopener\">emergency department: A retrospective study\u003C/a>. Paediatr Child Health. 2023;28(1):30-6.\u003C/li>\n\u003Cli>Orhan MF, Büyükavci M. \u003Ca href=\"https://pubmed.ncbi.nlm.nih.gov/36161971/\" target=\"_blank\" rel=\"noopener\">Intravenous iron therapy for \u003C/a>\u003Ca href=\"https://pubmed.ncbi.nlm.nih.gov/34557594/\" target=\"_blank\" rel=\"noopener\">children\u003C/a>\u003Ca href=\"https://pubmed.ncbi.nlm.nih.gov/36161971/\" target=\"_blank\" rel=\"noopener\"> with iron deficiency anemia\u003C/a>. J Pediatr Hematol Oncol. 2023;45(1):e56-e9.\u003C/li>\n\u003Cli>McEvoy MT, Stuckert AJ, Castellanos MI, et al. \u003Ca href=\"https://pubmed.ncbi.nlm.nih.gov/36579803/\" target=\"_blank\" rel=\"noopener\">Management of nutritional iron deficiency anemia\u003C/a> \u003Ca href=\"https://pubmed.ncbi.nlm.nih.gov/36579803/\" target=\"_blank\" rel=\"noopener\">for young children in the emergency department\u003C/a>. Pediatr Blood Cancer. 2023;70(3):e30181.\u003C/li>\n\u003Cli>Panagopoulou P, Alexiadou S, Ntoumpara M, et al. \u003Ca href=\"https://pubmed.ncbi.nlm.nih.gov/35083718/\" target=\"_blank\" rel=\"noopener\">Safety of ferric carboxymaltose in children\u003C/a>: \u003Ca href=\"https://pubmed.ncbi.nlm.nih.gov/35083718/\" target=\"_blank\" rel=\"noopener\">Report of a case series from Greece and review of the literature\u003C/a>. Paediatr Drugs. 2022;24(2):137- 46.\u003C/li>\n\u003Cli>Baig AMM, Batool S, Aslam T, et al. \u003Ca href=\"https://pubmed.ncbi.nlm.nih.gov/35576294/\" target=\"_blank\" rel=\"noopener\">Efficacy and safety of intravenous iron in children with iron\u003C/a> \u003Ca href=\"https://pubmed.ncbi.nlm.nih.gov/35576294/\" target=\"_blank\" rel=\"noopener\">deficiency anaemia poorly compliant to oral iron therapy\u003C/a>. J Ayub Med Coll Abbottabad. 2022;34(2):317-20.\u003C/li>\n\u003Cli>van den Akker M, Chielens L, Lopes L, et al. \u003Ca href=\"https://pubmed.ncbi.nlm.nih.gov/34557594/\">Thrombocytopenia in severe iron deficiency anemia in children.\u003C/a> Health Sci Rep. 2021;4(3):e351.\u003C/li>\n\u003Cli>Boucher AA, Bedel A, Jones S, et al. \u003Ca href=\"https://pubmed.ncbi.nlm.nih.gov/33769677/\" target=\"_blank\" rel=\"noopener\">A retrospective study of the safety and efficacy of low\u003C/a> \u003Ca href=\"https://pubmed.ncbi.nlm.nih.gov/33769677/\" target=\"_blank\" rel=\"noopener\">molecular weight iron dextran for children with iron deficiency anemia\u003C/a>. Pediatr Blood Cancer. 2021;68(7):e29024.\u003C/li>\n\u003Cli>Stoffel NU, Zeder C, Brittenham GM, et al. \u003Ca href=\"https://pubmed.ncbi.nlm.nih.gov/31413088/\" target=\"_blank\" rel=\"noopener\">Iron absorption from supplements is greater with\u003C/a> \u003Ca href=\"https://pubmed.ncbi.nlm.nih.gov/31413088/\" target=\"_blank\" rel=\"noopener\">alternate day than with consecutive day dosing in iron-deficient anemic women\u003C/a>. Haematologica. 2020;105(5):1232-9.\u003C/li>\n\u003Cli>Russo G, Guardabasso V, Romano F, et al. \u003Ca href=\"https://pubmed.ncbi.nlm.nih.gov/31965272/\" target=\"_blank\" rel=\"noopener\">Monitoring oral iron therapy in children with iron\u003C/a> \u003Ca href=\"https://pubmed.ncbi.nlm.nih.gov/31965272/\" target=\"_blank\" rel=\"noopener\">deficiency anemia: An observational, prospective, multicenter study of AIEOP patients\u003C/a> (Associazione Italiana Emato-oncologia Pediatrica). Ann Hematol. 2020;99(3):413-20.\u003C/li>\n\u003Cli>Powers JM, Nagel M, Raphael JL, et al. \u003Ca href=\"https://pubmed.ncbi.nlm.nih.gov/32014276/\">Barriers to and facilitators of iron therapy in children with iron deficiency anemia.\u003C/a> J Pediatr. 2020;219:202-8.\u003C/li>\n\u003Cli>Kaundal R, Bhatia P, Jain A, et al. \u003Ca href=\"https://pubmed.ncbi.nlm.nih.gov/31811360/\" target=\"_blank\" rel=\"noopener\">Randomized controlled trial of twice-daily versus alternate-day\u003C/a> \u003Ca href=\"https://pubmed.ncbi.nlm.nih.gov/31811360/\" target=\"_blank\" rel=\"noopener\">oral iron therapy in the treatment of iron-deficiency anemia\u003C/a>. Ann Hematol. 2020;99(1):57-63.\u003C/li>\n\u003Cli>Sabe R, Vatsayan A, Mahran A, et al. \u003Ca href=\"https://pubmed.ncbi.nlm.nih.gov/31453270/\" target=\"_blank\" rel=\"noopener\">Safety and efficacy of intravenous iron sucrose for iron-\u003C/a> \u003Ca href=\"https://pubmed.ncbi.nlm.nih.gov/31453270/\" target=\"_blank\" rel=\"noopener\">deficiency anemia in children and adolescents with inflammatory bowel disease\u003C/a>. Glob Pediatr Health. 2019;6:2333794×19870981.\u003C/li>\n\u003Cli>Patil P, Geevarghese P, Khaire P, et al. \u003Ca href=\"https://pubmed.ncbi.nlm.nih.gov/31520309/\" target=\"_blank\" rel=\"noopener\">Comparison of therapeutic efficacy of ferrous ascorbate\u003C/a> \u003Ca href=\"https://pubmed.ncbi.nlm.nih.gov/31520309/\" target=\"_blank\" rel=\"noopener\">and iron polymaltose complex in \u003C/a>\u003Ca href=\"https://pubmed.ncbi.nlm.nih.gov/20404750/\" target=\"_blank\" rel=\"noopener\">iron deficiency anemia in children\u003C/a>\u003Ca href=\"https://pubmed.ncbi.nlm.nih.gov/31520309/\" target=\"_blank\" rel=\"noopener\">: A randomized controlled trial\u003C/a>. Indian J Pediatr. 2019;86(12):1112-7.\u003C/li>\n\u003Cli>Maiti D, Acharya S, Basu S. \u003Ca href=\"https://pubmed.ncbi.nlm.nih.gov/31041221/\" target=\"_blank\" rel=\"noopener\">Recognizing missed opportunities to diagnose and treat iron deficiency\u003C/a> \u003Ca href=\"https://pubmed.ncbi.nlm.nih.gov/31041221/\" target=\"_blank\" rel=\"noopener\">anemia: A study based on prevalence of anemia among children in a teaching hospital\u003C/a>. J Family Med Prim Care. 2019;8(3):899-903.\u003C/li>\n\u003Cli>Jang HN, Yoon HS, Lee EH. \u003Ca href=\"https://pubmed.ncbi.nlm.nih.gov/31484495/\" target=\"_blank\" rel=\"noopener\">Prospective case control study of iron deficiency and the risk of febrile\u003C/a> \u003Ca href=\"https://pubmed.ncbi.nlm.nih.gov/31484495/\" target=\"_blank\" rel=\"noopener\">seizures in children in South Korea\u003C/a>. BMC Pediatr. 2019;19(1):309.\u003C/li>\n\u003Cli>Vossoughi S, Perez G, Whitaker BI, et al. \u003Ca href=\"https://pubmed.ncbi.nlm.nih.gov/28948619/\" target=\"_blank\" rel=\"noopener\">Analysis of pediatric adverse reactions to transfusions\u003C/a>. Transfusion. 2018;58(1):60-9.\u003C/li>\n\u003Cli>Stein RE, Plantz K, Maxwell EC, et al. \u003Ca href=\"https://pubmed.ncbi.nlm.nih.gov/28704225/\" target=\"_blank\" rel=\"noopener\">Intravenous iron sucrose for treatment of iron deficiency\u003C/a> \u003Ca href=\"https://pubmed.ncbi.nlm.nih.gov/28704225/\" target=\"_blank\" rel=\"noopener\">anemia in pediatric inflammatory bowel disease\u003C/a>. J Pediatr Gastroenterol Nutr. 2018;66(2):e51-e5.\u003C/li>\n\u003Cli>Boucher AA, Pfeiffer A, Bedel A, et al. \u003Ca href=\"https://pubmed.ncbi.nlm.nih.gov/29369486/\" target=\"_blank\" rel=\"noopener\">Utilization trends and safety of intravenous iron replacement\u003C/a> \u003Ca href=\"https://pubmed.ncbi.nlm.nih.gov/29369486/\" target=\"_blank\" rel=\"noopener\">in pediatric specialty care: A large retrospective cohort study\u003C/a>. Pediatr Blood Cancer. 2018;65(6):e26995.\u003C/li>\n\u003Cli>Tan MLN, Windscheif PM, Thornton G, et al. \u003Ca href=\"https://pubmed.ncbi.nlm.nih.gov/28844092/\">Retrospective review of effectiveness and safety of intravenous ferric carboxymaltose given to children with iron deficiency anaemia in one UK tertiary centre.\u003C/a> Eur J Pediatr. 2017;176(10):1419-23.\u003C/li>\n\u003Cli>Powers JM, Shamoun M, McCavit TL, et al. \u003Ca href=\"https://pubmed.ncbi.nlm.nih.gov/27776750/\" target=\"_blank\" rel=\"noopener\">Intravenous ferric carboxymaltose in children with iron\u003C/a> \u003Ca href=\"https://pubmed.ncbi.nlm.nih.gov/27776750/\" target=\"_blank\" rel=\"noopener\">deficiency anemia who respond poorly to oral iron\u003C/a>. J Pediatr. 2017;180:212-6.\u003C/li>\n\u003Cli>Powers JM, Buchanan GR, Adix L, et al. \u003Ca href=\"https://pubmed.ncbi.nlm.nih.gov/28609534/\" target=\"_blank\" rel=\"noopener\">Effect of low-dose ferrous sulfate vs iron polysaccharide\u003C/a> \u003Ca href=\"https://pubmed.ncbi.nlm.nih.gov/28609534/\" target=\"_blank\" rel=\"noopener\">complex on hemoglobin concentration in young children with nutritional iron-deficiency anemia: A\u003C/a> \u003Ca href=\"https://pubmed.ncbi.nlm.nih.gov/28609534/\" target=\"_blank\" rel=\"noopener\">randomized clinical trial\u003C/a>. JAMA. 2017;317(22):2297-304.\u003C/li>\n\u003Cli>Okam MM, Koch TA, Tran MH. \u003Ca href=\"https://pubmed.ncbi.nlm.nih.gov/28454902/\" target=\"_blank\" rel=\"noopener\">Iron supplementation, response in iron-deficiency anemia: Analysis\u003C/a> \u003Ca href=\"https://pubmed.ncbi.nlm.nih.gov/28454902/\" target=\"_blank\" rel=\"noopener\">of five trials\u003C/a>. Am J Med. 2017;130(8):991.e1-.e8.\u003C/li>\n\u003Cli>Kaneva K, Chow E, Rosenfield CG, Kelly MJ. \u003Ca href=\"https://pubmed.ncbi.nlm.nih.gov/25754747/\">Intravenous iron sucrose for children with iron deficiency anemia.\u003C/a> J Pediatr Hematol Oncol. 2017;39(5):e259-e62.\u003C/li>\n\u003Cli>Cooke AG, McCavit TL, Buchanan GR, Powers JM. \u003Ca href=\"https://pubmed.ncbi.nlm.nih.gov/24972460/\" target=\"_blank\" rel=\"noopener\">Iron deficiency\u003C/a>\u003Ca href=\"https://pubmed.ncbi.nlm.nih.gov/27789349/\" target=\"_blank\" rel=\"noopener\"> anemia in adolescents who\u003C/a> \u003Ca href=\"https://pubmed.ncbi.nlm.nih.gov/27789349/\" target=\"_blank\" rel=\"noopener\">present with heavy menstrual bleeding\u003C/a>. J Pediatr Adolesc Gynecol. 2017;30(2):247-50.\u003C/li>\n\u003Cli>Carvalho FSG, de Medeiros IA, Antunes H. \u003Ca href=\"https://pubmed.ncbi.nlm.nih.gov/28643539/\" target=\"_blank\" rel=\"noopener\">Prevalence of iron deficiency anemia and iron\u003C/a> \u003Ca href=\"https://pubmed.ncbi.nlm.nih.gov/28643539/\" target=\"_blank\" rel=\"noopener\">deficiency in a pediatric population with inflammatory bowel disease\u003C/a>. Scand J Gastroenterol. 2017;52(10):1099-103.\u003C/li>\n\u003Cli>Powers JM, Daniel CL, McCavit TL, Buchanan GR. \u003Ca href=\"https://pubmed.ncbi.nlm.nih.gov/26728130/\" target=\"_blank\" rel=\"noopener\">Deficiencies in the management of iron\u003C/a> \u003Ca href=\"https://pubmed.ncbi.nlm.nih.gov/26728130/\" target=\"_blank\" rel=\"noopener\">deficiency anemia during childhood\u003C/a>. Pediatr Blood Cancer. 2016;63(4):743-5.\u003C/li>\n\u003Cli>Mantadakis E, Tsouvala E, Xanthopoulou V, Chatzimichael A. \u003Ca href=\"https://pubmed.ncbi.nlm.nih.gov/25754747/\">Intravenous iron sucrose for children with iron deficiency anemia: A single institution study.\u003C/a> World J Pediatr. 2016;12(1):109-13.\u003C/li>\n\u003Cli>Joo EY, Kim KY, Kim DH, et al. \u003Ca href=\"https://pubmed.ncbi.nlm.nih.gov/28090490/\" target=\"_blank\" rel=\"noopener\">Iron deficiency anemia in infants and toddlers\u003C/a>. Blood Res. 2016;51(4):268-73.\u003C/li>\n\u003Cli>Oakley FD, Woods M, Arnold S, Young PP. \u003Ca href=\"https://pubmed.ncbi.nlm.nih.gov/25145580/\" target=\"_blank\" rel=\"noopener\">Transfusion reactions in pediatric compared with adult\u003C/a> \u003Ca href=\"https://pubmed.ncbi.nlm.nih.gov/25145580/\" target=\"_blank\" rel=\"noopener\">patients: A look at rate, reaction type, and associated products\u003C/a>. Transfusion. 2015;55(3):563-70.\u003C/li>\n\u003Cli>Crary SE, Hall K, Buchanan GR. \u003Ca href=\"https://pubmed.ncbi.nlm.nih.gov/21298748/\" target=\"_blank\" rel=\"noopener\">Intravenous iron sucrose for children with iron deficiency failing to\u003C/a> \u003Ca href=\"https://pubmed.ncbi.nlm.nih.gov/21298748/\" target=\"_blank\" rel=\"noopener\">respond to oral iron therapy\u003C/a>. Pediatr Blood Cancer. 2011;56(4):615-9.\u003C/li>\n\u003Cli>Abdullah K ZS, Parkin P, Grenier D. \u003Ca href=\"https://cpsp.cps.ca/uploads/publications/RA-iron-deficiency-anemia.pdf.\" target=\"_blank\" rel=\"noopener\">Iron-deficiency anemia in children. Canadian Pediatric Society\u003C/a> \u003Ca href=\"https://cpsp.cps.ca/uploads/publications/RA-iron-deficiency-anemia.pdf.\" target=\"_blank\" rel=\"noopener\">Surveillance Program\u003C/a>. 2011.\u003C/li>\n\u003Cli>Huang SC, Yang YJ, Cheng CN, et al. \u003Ca href=\"https://pubmed.ncbi.nlm.nih.gov/20404750/\">The etiology and treatment outcome of iron deficiency and iron deficiency anemia in children.\u003C/a> J Pediatr Hematol Oncol. 2010;32(4):282-5.\u003C/li>\n\u003Cli>Baker RD, Greer FR. \u003Ca href=\"https://pubmed.ncbi.nlm.nih.gov/20923825/\" target=\"_blank\" rel=\"noopener\">Diagnosis and prevention of iron deficiency and iron-deficiency anemia in\u003C/a> \u003Ca href=\"https://pubmed.ncbi.nlm.nih.gov/20923825/\" target=\"_blank\" rel=\"noopener\">infants and young children (0-3 years of age)\u003C/a>. Pediatrics. 2010;126(5):1040-50.\u003C/li>\n\u003Cli>Pinsk V, Levy J, Moser A, et al. \u003Ca href=\"https://pubmed.ncbi.nlm.nih.gov/18605353/\" target=\"_blank\" rel=\"noopener\">Efficacy and safety of intravenous iron sucrose therapy in a group\u003C/a> \u003Ca href=\"https://pubmed.ncbi.nlm.nih.gov/18605353/\" target=\"_blank\" rel=\"noopener\">of children with iron deficiency anemia\u003C/a>. Isr Med Assoc J. 2008;10(5):335-8.\u003C/li>\n\u003Cli>Berard R, Matsui D, Lynch T. \u003Ca href=\"https://pubmed.ncbi.nlm.nih.gov/17505267/\" target=\"_blank\" rel=\"noopener\">Screening for iron deficiency anemia in at risk children in the pediatric\u003C/a> \u003Ca href=\"https://pubmed.ncbi.nlm.nih.gov/17505267/\" target=\"_blank\" rel=\"noopener\">emergency department: A survey of Canadian pediatric emergency department physicians\u003C/a>. Pediatr Emerg Care. 2007;23(5):281-4.\u003C/li>\n\u003Cli>Pusic MV, Dawyduk BJ, Mitchell D. \u003Ca href=\"https://pubmed.ncbi.nlm.nih.gov/16300683/\" target=\"_blank\" rel=\"noopener\">Opportunistic screening for iron-deficiency in 6-36 month old\u003C/a> \u003Ca href=\"https://pubmed.ncbi.nlm.nih.gov/16300683/\" target=\"_blank\" rel=\"noopener\">children presenting to the paediatric emergency department\u003C/a>. BMC Pediatr. 2005;5:42.\u003C/li>\n\u003Cli>Zlotkin S, Arthur P, Antwi KY, Yeung G. \u003Ca href=\"https://pubmed.ncbi.nlm.nih.gov/11533326/\" target=\"_blank\" rel=\"noopener\">Randomized, controlled trial of single versus 3-times-daily\u003C/a> \u003Ca href=\"https://pubmed.ncbi.nlm.nih.gov/11533326/\" target=\"_blank\" rel=\"noopener\">ferrous sulfate drops for treatment of anemia\u003C/a>. 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