Key Study: Early reversal of pediatric-neonatal septic shock by community physicians is associated with improved outcome (2003)

Key Study: Early reversal of pediatric-neonatal septic shock by community physicians is associated with improved outcome (2003)

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Objective: Experimental and clinical studies of septic shock support the concept that early resuscitation with fluid and inotropic therapies improves survival in a time-dependent manner. The new American College of Critical Care Medicine-Pediatric Advanced Life Support (ACCM-PALS) Guidelines for hemodynamic support of newborns and children in septic shock recommend this therapeutic approach. The objective of this study was to determine whether early septic shock reversal and use of resuscitation practice consistent with the new ACCM-PALS Guidelines by community physicians is associated with improved outcome. Published: 2003.