Cochrane Systematic Review: Human recombinant protein C for severe sepsis and septic shock in adult and paediatric patients (2012)

Cochrane Systematic Review: Human recombinant protein C for severe sepsis and septic shock in adult and paediatric patients (2012)

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Background: Sepsis is a common and frequently fatal condition. Human recombinant activated protein C (APC) has been introduced to reduce the high risk of death associated with severe sepsis or septic shock. This systematic review is an update of a Cochrane review originally published in 2007.Objectives: We assessed the benefits and harms of APC for patients with severe sepsis or septic shock. Published: 2012.