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Early predictors of unresponsiveness to high-flow nasal cannula therapy in a pediatric emergency department.

Early predictors of unresponsiveness to high-flow nasal cannula therapy in a pediatric emergency department.

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High-flow nasal cannula (HFNC) is a new treatment option for pediatric respiratory distress and we aimed to assess early predictive factors of unresponsiveness to HFNC therapy in a pediatric emergency department (ED). The low initial SpO2 and SF ratio, respiratory acidosis, and SF ratio less than 195 at the first hours of treatment were related to unresponsiveness to HFNC therapy in our pediatric emergency department.