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A Randomized Trial of High-Flow Oxygen Therapy in Infants with Bronchiolitis.

A Randomized Trial of High-Flow Oxygen Therapy in Infants with Bronchiolitis.

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High-flow oxygen therapy through a nasal cannula has been increasingly used in infants with bronchiolitis, despite limited high-quality evidence of its efficacy. The efficacy of high-flow oxygen therapy through a nasal cannula in settings other than intensive care units (ICUs) is unclear. Among infants with bronchiolitis who were treated outside an ICU, those who received high-flow oxygen therapy had significantly lower rates of escalation of care due to treatment failure than those in the group that received standard oxygen therapy.