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Key study: How fast does oral dexamethasone work in mild to moderately severe croup? A randomized double-blinded clinical trial

Key study: How fast does oral dexamethasone work in mild to moderately severe croup? A randomized double-blinded clinical trial

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Objective: For children with croup controversy remains over dosage and time to onset of action of oral steroids. The Cochrane Collaboration and other reviews have suggested 0.6 mg/kg dexamethasone be used (despite some evidence that 0.15 mg/kg is effective) with no expectation of benefit before 4-6 h. This randomized double-blinded clinical trial examines whether 0.15 mg/kg dexamethasone works by 30 min. Published: 2012.