Croup is a common respiratory illness caused by a viral infection in the airway. Accompanied by a barky cough and respiratory distress, this illness is most common in children aged birth to 6 years, peaking at 2 years of age.



Summaries of systematic reviews

Cochrane Summary: Nebulized epinephrine for croup in children


Bjornson, C, Russell, K, Vandermeer, B, Klassen, TP, Johnson, DW,

Objective: To assess the efficacy (measured by croup scores, rate of intubation and health care utilization such as rate of hospitalization) and safety (frequency and severity of side effects) of nebulized epinephrine versus placebo in children with croup, evaluated in an emergency department (ED) or hospital setting. Published online: October 2013; Evidence current to: July 2013.

Cochrane Summary: Glucocorticoids for croup


Russell, K, Liang, Y, O'Gorman, K, Johnson, DW, Klassen, TP,

Objective: To provide evidence to guide clinicians in their treatment of patients with croup by determining the effectiveness of glucocorticoids and to identify areas requiring future research. Published online: January 2012; Evidence current to: July 2010.

Overviews of systematic reviews

Cochrane Overview: The Cochrane Library and the treatment of croup in children: an overview of reviews (2010)


Bjornson, C, Russell, K, Foisy, M, Johnson, D,

Objective: To synthesize the evidence currently in the Cochrane Database of Systematic Reviews (CDSR) related to the clinical effectiveness and applicability of four treatments for croup - glucocorticoids, epinephrine, heliox and humidified air. Published: December 2010.

Cochrane Overview: Evidence Summary: Croup


Alberta Research Centre for Health Evidence (ARCHE),

The purpose of this document is to describe the effectiveness of four treatment options, based on a 2012 Overview of Reviews. Published online: 2014.