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Streptococcal Infections Cochrane Pediatric Emergency Medicine Reviews

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Cochrane Systematic Review: Different antibiotic treatments for group A streptococcal pharyngitis

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van Driel ML, De Sutter AI, Keber N, Habraken H, Christiaens T.

Objectives: To assess the evidence on the comparative efficacy of different antibiotics in: (a) alleviating symptoms (pain, fever); (b) shortening the duration of the illness; (c) preventing relapse; and (d) preventing complications (suppurative complications, acute rheumatic fever, post-streptococcal glomerulonephritis). To assess the evidence on the comparative incidence of adverse effects and the risk-benefit of antibiotic treatment for streptococcal pharyngitis.

Cochrane Systematic Review: Short-term late-generation antibiotics versus longer term penicillin for acute streptococcal pharyngitis in children

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Altamimi S, Khalil A, Khalaiwi KA, Milner RA, Pusic MV, Al Othman MA.

Objectives: To summarize the evidence regarding the efficacy of two to six days of newer oral antibiotics (short duration) compared to 10 days of oral penicillin (standard duration) in treating children with acute GABHS pharyngitis.