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Malaria Cochrane Pediatric Emergency Medicine Reviews

Browse Cochrane Pediatric Emergency Medicine Reviews

 


Cochrane Systematic Review: Rapid diagnostic tests for diagnosing uncomplicated P. falciparum malaria in endemic countries

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Abba K, Deeks JJ, Olliaro P, Naing CM, Jackson SM, Takwoingi Y, Donegan S, G...

OBJECTIVES: To assess the diagnostic accuracy of RDTs for detecting P. falciparum parasitaemia in persons living in endemic areas who present to ambulatory healthcare facilities with symptoms suggestive of malaria by type and brand.

Cochrane Systematic Review: Artemisinin derivatives for treating uncomplicated malaria

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McIntosh HM, Olliaro P

OBJECTIVES: The objective of this review was to assess the effects of artemisinin drugs for treating uncomplicated falciparum malaria.

Cochrane Systematic Review: Chloroquine or amodiaquine combined with sulfadoxine-pyrimethamine for treating uncomplicated malaria

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McIntosh HM, Jones KL

OBJECTIVES: To assess the combination of CQ or AQ plus SP compared with SP alone for first-line treatment of uncomplicated falciparum malaria.

Cochrane Systematic Review: Artemisinin derivatives for treating severe malaria

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McIntosh HM, Olliaro P

OBJECTIVES: The objective of this review was to assess the effects of artemisinin drugs for severe and complicated falciparum malaria in adults and children.

Cochrane Systematic Review: Steroids for treating cerebral malaria

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Prasad K, Garner P

OBJECTIVES: This review aimed to assess the effects of steroids in patients with cerebral malaria in relation to survival and long-term disability.

Cochrane Systematic Review: Iron-chelating agents for treating malaria

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Smith HJ, Meremikwu M

OBJECTIVES: To assess the effects of iron-chelating agents combined with antimalarial drugs, or iron chelators alone, for treating Plasmodium falciparum malaria in adults and children, in relation to mortality, coma recovery time, parasite clearance, and adverse effects.

Cochrane Systematic Review: Blood transfusion for treating malarial anaemia

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Meremikwu M, Smith HJ

OBJECTIVES: This review evaluates the effects of routine blood transfusion for severe anaemia on death and adverse outcomes in malarious areas.

Cochrane Systematic Review: Antipyretic measures for treating fever in malaria

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Meremikwu MM, Odigwe CC, Akudo Nwagbara B, Udoh EE

OBJECTIVES: We aimed to assess whether treatments to reduce fever in malaria influence the course of the illness.

Cochrane Systematic Review: Azithromycin for treating uncomplicated malaria

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van Eijk AM, Terlouw DJ

OBJECTIVES: To compare the use of azithromycin alone or in combination with other antimalarial drugs with the use of alternative antimalarial drugs for treating uncomplicated malaria caused by Plasmodium falciparum or Plasmodium vivax.

Cochrane Systematic Review: Chlorproguanil-dapsone for treating uncomplicated malaria

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Bukirwa H, Garner P, Critchley J

OBJECTIVES: To compare chlorproguanil-dapsone with other antimalarial drugs for treating uncomplicated falciparum malaria.

Cochrane Systematic Review: Intramuscular arteether for treating severe malaria

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Afolabi BB, Okoromah CN

OBJECTIVES: To compare intramuscular arteether with other antimalarial drugs to treat severe malaria.

Cochrane Systematic Review: Atovaquone-proguanil for treating uncomplicated malaria

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Osei-Akoto A, Orton L, Owusu-Ofori SP

OBJECTIVES: To compare atovaquone-proguanil with other antimalarial drugs (alone or in combination) for treating children and adults with uncomplicated Plasmodium falciparum malaria.

Cochrane Systematic Review: Sulfadoxine-pyrimethamine plus artesunate versus sulfadoxine-pyrimethamine plus amodiaquine for treating uncomplicated malaria

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Bukirwa H, Critchley J

OBJECTIVES: To compare sulfadoxine-pyrimethamine plus amodiaquine (SP plus AQ) with sulfadoxine-pyrimethamine plus artesunate (SP plus AS) for treating uncomplicated Plasmodium falciparum malaria.

Cochrane Systematic Review: Artesunate versus quinine for treating severe malaria

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Sinclair D, Donegan S, Isba R, Lalloo DG

OBJECTIVES: To compare artesunate with quinine for treating severe malaria.

Cochrane Systematic Review: Drugs for preventing malaria in travellers

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Jacquerioz FA, Croft AM

OBJECTIVES: To compare the effects of currently used antimalaria drugs when given as prophylaxis to non-immune adult and child travellers who are travelling to regions with Plasmodium falciparum resistance to chloroquine. Specifically, to assess the efficacy, safety, and tolerability of atovaquone-proguanil, doxycycline, and mefloquine compared to each other, and also when compared to chloroquine-proguanil and to primaquine.

Cochrane Systematic Review: High first dose quinine regimen for treating severe malaria

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Lesi A, Meremikwu M

OBJECTIVES: To assess the clinical outcomes and adverse events of a high first (loading) dose regimen of quinine compared with a uniform (no loading) dose regimen in people with severe malaria.

Cochrane Systematic Review: Mannitol and other osmotic diuretics as adjuncts for treating cerebral malaria

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Okoromah CA, Afolabi BB, Wall EC

OBJECTIVES: To compare mannitol or urea to placebo or no diuretic for treating children or adults with cerebral malaria.