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Anemia, Sickle Cell Cochrane Pediatric Emergency Medicine Reviews

Browse Cochrane Pediatric Emergency Medicine Reviews

 


Cochrane Systematic Review: Neonatal screening for sickle cell disease

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Lees CM, Davies S, Dezateux C

OBJECTIVES: To assess whether there is evidence that neonatal screening for sickle cell disease rather than symptomatic diagnosis reduces adverse short and long term outcomes for those in whom the disease is detected, without adverse outcomes in the population screened.

Cochrane Systematic Review: Blood transfusion for preventing stroke in people with sickle cell disease

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Wang WC, Dwan K

OBJECTIVES: To assess risks and benefits of chronic blood transfusion regimens in people with sickle cell disease to prevent first stroke or recurrences.

Cochrane Systematic Review: Antibiotics for treating community acquired pneumonia in people with sickle cell disease

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Mart-Carvajal AJ, Conterno LO

OBJECTIVES: To determine the efficacy and safety of the antibiotic treatment approaches (monotherapy or combined) for people with sickle cell disease suffering from community-acquired pneumonia.

Cochrane Systematic Review: Inhaled nitric oxide for acute chest syndrome in people with sickle cell disease

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Al Hajeri A, Serjeant GR, Fedorowicz Z

OBJECTIVES: To assess the effectiveness of inhaled nitric oxide for treating acute chest syndrome by comparing improvement in symptoms and clinical outcomes against standard care.

Cochrane Systematic Review: Blood transfusions for treating acute chest syndrome in people with sickle cell disease

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Alhashimi D, Fedorowicz Z, Alhashimi F, Dastgiri S

OBJECTIVES: To assess the effectiveness of blood transfusions, simple and exchange, for treating ACS by comparing improvement in symptoms and clinical outcomes against standard care.

Cochrane Systematic Review: Angiotensin-converting enzyme (ACE) inhibitors for proteinuria and microalbuminuria in people with sickle cell disease

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Sasongko TH, Nagalla S, Ballas SK

OBJECTIVES: To determine the effectiveness of ACE inhibitor administration in people with sickle cell disease for decreasing intraglomerular pressure, microalbuminuria and proteinuria and to to assess the safety of ACE inhibitors as pertains to their adverse effects.